methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

Base Information

Chemical Name:methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate
CAS No.:1001195-62-5
Molecular Formula:C₁₆H₁₃FO₄
Molecular Weight:288.275
Hs Code.:

Synonyms:methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

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Technology Process of methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

There total 6 articles about methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 392-04-1
methyl 4-fluoro-2-hydroxybenzoate

: 103-80-0
phenylacetyl chloride

: 1001195-62-5
methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

Guidance literature:: methyl 4-fluoro-2-hydroxybenzoate; phenylacetyl chloride; aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃; for 16.1667h;

With hydrogenchloride; water; In dichloromethane;

Reference yield:

: 1384440-37-2
C₁₆H₁₂FNO₆

: 1001195-62-5
methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

Guidance literature:: C₁₆H₁₂FNO₆; With hydrogen; In tetrahydrofuran; at 20 ℃; for 3h;

With nitrosonium tetrafluoroborate; In acetonitrile; at 0 ℃; for 2.5h;
DOI:10.1016/j.bmcl.2012.04.121

Reference yield:

: 345-29-9
4-fluorosalicylic acid

: 103-80-0
phenylacetyl chloride

: 1001195-62-5
methyl 4-fluoro-2-hydroxy-5-phenylacetylbenzoate

Guidance literature:: 4-fluorosalicylic acid; phenylacetyl chloride; With aluminum (III) chloride; In dichloromethane; at 0 - 20 ℃;

With hydrogenchloride; at 0 ℃;
DOI:10.1016/j.bmcl.2012.04.121