Chemical Property of Oxiracetam
Chemical Property:
- Appearance/Colour:white crystalline powder
- Vapor Pressure:7.39E-12mmHg at 25°C
- Melting Point:165-168 °C
- Refractive Index:1.57
- Boiling Point:494.6 °C at 760 mmHg
- PKA:13.76±0.20(Predicted)
- Flash Point:252.9 °C
- PSA：83.63000
- Density:1.416 g/cm3
- LogP:-1.29690
- Storage Temp.:2-8°C
- Solubility.:DMSO (Slightly, Heated), Methanol (Slightly, Heated)
- XLogP3:-2.2
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:3
- Rotatable Bond Count:2
- Exact Mass:158.06914219
- Heavy Atom Count:11
- Complexity:192
- Purity/Quality:
-
99% *data from raw suppliers
Oxiracetam *data from reagent suppliers
Safty Information:
- Pictogram(s):
Xi
- Hazard Codes:Xi
- Statements:
36/38
- Safety Statements:
26-36
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:C1C(CN(C1=O)CC(=O)N)O
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Description
Oxiracetam is a structural analogue of piracetam. Oxiracetam has enhancing effects on vigilance and memory. In comparison with piracetam, oxiracetam exhibits greater improvement in memory (Itil et al., 1986) and has been used extensively for the treatment of dementia, including AD, VaD, MID (Baumel et al., 1989; Dysken et al., 1989), and mixed forms. Green et al. (1992) failed to demonstrate a difference from placebo in AD patients. In contrast, Maina et al. (1989) studied 289 patients with MID in a double-blind placebo-controlled trial and after 12 weeks of treatment found that oxiracetam reduced behavioural symptoms.
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Uses
Oxiracetam is a 4-hydroxy analog of piracetam with psychostimulant activity, reportedly useful in relieving the symptoms of cerebral insufficiency in the elderly.
