2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

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Chemical Name:2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one
CAS No.:1227153-71-0
Molecular Formula:C₂₇H₃₂ClN₃O₅
Molecular Weight:514.021
Hs Code.:

Synonyms:2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

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Chemical Property of 2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

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Technology Process of 2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

There total 1 articles about 2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

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: 1227152-72-8
2-(1-{[5-(benzyloxy)-2-chlorophenyl]carbonyl}piperidin-4-yl)-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

: 75-03-6
ethyl iodide

: 1227153-71-0
2-{1-[(2-chloro-5-ethoxyphenyl)carbonyl]piperidin-4-yl}-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one

Guidance literature:: 2-(1-{[5-(benzyloxy)-2-chlorophenyl]carbonyl}piperidin-4-yl)-5-(3,4-dimethoxyphenyl)-4,4-dimethyl-2,4-dihydro-3H-pyrazol-3-one; With ammonium formate; palladium 10% on activated carbon; In methanol; Inert atmosphere; Reflux;

ethyl iodide; With potassium carbonate; In dimethyl sulfoxide; at 55 ℃; for 3.5h; Inert atmosphere;