(RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Base Information

Chemical Name:(RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne
CAS No.:116503-87-8
Molecular Formula:C₄₄H₅₂O₂SSi₂
Molecular Weight:701.133
Hs Code.:

Synonyms:(RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Suppliers and Price of (RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

There total 6 articles about (RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 116503-81-2
(RS,SR)-1,2-bis[{[(1,1-dimethylethyl)diphenylsilyl]oxy}methyl]-4-cyclohexene

: 116503-87-8
(RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Guidance literature:: Multi-step reaction with 6 steps

1: 1.) O₃, 2.) (MeO)3P / 1.) EtOAc-MeOH 1:1, -78 deg C, 2.) from -78 deg C to 25 deg C, 10 h

2: PPh₃ / CH₂Cl₂ / 8 h / 0 - 25 °C

3: 74 percent / n-BuLi / tetrahydrofuran / 1.25 h / -78 - 0 °C

4: 97 percent / DIBAL / CH₂Cl₂ / 6.5 h / -78 °C

5: P(oct)3, CBr₄ / diethyl ether / 1 h / 0 °C

6: 58 percent / Na₂S*9H₂O / ethanol; H₂O / 1.5 h / 78 °C

With sodium sulfide; n-butyllithium; carbon tetrabromide; TOP; diisobutylaluminium hydride; ozone; triphenylphosphine; phosphorous acid trimethyl ester; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;
DOI:10.1021/ja00229a068

Reference yield:

: 116503-82-3
(3R,4S)-3,4-Bis-(tert-butyl-diphenyl-silanyloxymethyl)-hexanedial

: 116503-87-8
(RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Guidance literature:: Multi-step reaction with 5 steps

1: PPh₃ / CH₂Cl₂ / 8 h / 0 - 25 °C

2: 74 percent / n-BuLi / tetrahydrofuran / 1.25 h / -78 - 0 °C

3: 97 percent / DIBAL / CH₂Cl₂ / 6.5 h / -78 °C

4: P(oct)3, CBr₄ / diethyl ether / 1 h / 0 °C

5: 58 percent / Na₂S*9H₂O / ethanol; H₂O / 1.5 h / 78 °C

With sodium sulfide; n-butyllithium; carbon tetrabromide; TOP; diisobutylaluminium hydride; triphenylphosphine; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane; water;
DOI:10.1021/ja00229a068

Reference yield:

: 116503-85-6
(RS,SR)-5,6-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>-2,8-decadiyne-1,10-diol

: 116503-87-8
(RS,SR)-6,7-bis<<<(1,1-dimethylethyl)diphenylsilyl>oxy>methyl>thiacycloundeca-3,9-diyne

Guidance literature:: Multi-step reaction with 2 steps

1: P(oct)3, CBr₄ / diethyl ether / 1 h / 0 °C

2: 58 percent / Na₂S*9H₂O / ethanol; H₂O / 1.5 h / 78 °C

With sodium sulfide; carbon tetrabromide; TOP; In diethyl ether; ethanol; water;
DOI:10.1021/ja00229a068