3-PHENYL-3,4-DIHYDRO-2H-BENZO[E][1,3]OXAZINE

Base Information

• Chemical Name: 3-PHENYL-3,4-DIHYDRO-2H-BENZO[E][1,3]OXAZINE
• CAS No.: 51287-17-3
• Molecular Formula: C14H13NO
• Molecular Weight: 211.263
• Hs Code.: 2934999090
• Mol file: 51287-17-3.mol

Synonyms:3-phenyl-3,4-dihydro-1,3-benzoxazine;3-phenyl-3,4-dihydro-2H-1,3-benzoxazine;N-phenyl-3,4-dihydro-2H-1,3-benzoxazine;

Chemical Property of 3-PHENYL-3,4-DIHYDRO-2H-BENZO[E][1,3]OXAZINE

Chemical Property:

• Vapor Pressure: 2.34E-05mmHg at 25°C
• Boiling Point: 359.7°C at 760 mmHg
• Flash Point: 106.2°C
• PSA: 12.47000
• Density: 1.157g/cm³
• LogP: 3.10810

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-PHENYL-3,4-DIHYDRO-2H-BENZO[E][1,3]OXAZINE

There total 10 articles about 3-PHENYL-3,4-DIHYDRO-2H-BENZO[E][1,3]OXAZINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + aniline (62-53-3) + phenol (108-95-2,27073-41-2) → 3-phenyl-3,4-dihydro-2H-1,3-benzoxazine (51287-17-3)

Guidance literature:

With C₁₃H₁₄NO⁽¹⁺⁾*F₆P^(1-); for 0.25h; Reagent/catalyst; Catalytic behavior;

DOI:10.1080/00397911.2014.941503

Reference yield: 94.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-((phenylamino)methyl)phenol (3526-45-2) → 3-phenyl-3,4-dihydro-2H-1,3-benzoxazine (51287-17-3)

Guidance literature:

In ethanol; for 5h; Heating;

Reference yield: 72.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + aniline (62-53-3) + phenylboronic acid (98-80-6) → 3-phenyl-3,4-dihydro-2H-1,3-benzoxazine (51287-17-3)

Guidance literature:

With tert.-butylhydroperoxide; potassium carbonate; In dichloromethane; water; at 80 ℃; for 8h; Solvent; Sealed tube;

DOI:10.1016/j.tetlet.2017.02.081

upstream raw materials:

formaldehyd

2-((phenylamino)methyl)phenol

N-phenylsalicylaldimine

aniline

Downstream raw materials:

C₁₇H₂₁NOS

formaldehyd

2-((phenylamino)methyl)phenol

N-phenylsalicylaldimine