(Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone

Base Information

• Chemical Name: (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone
• CAS No.: 181765-57-1
• Molecular Formula: C₁₇H₁₃NO₂S₂
• Molecular Weight: 327.428
• Mol file: 181765-57-1.mol

Synonyms:(Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone

Chemical Property of (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone

There total 7 articles about (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.9%

2-thioxo-4-thiazolidinone (141-84-4) + p-benzyloxybenzaldehyde (4397-53-9) → (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone (181765-57-1,1055980-80-7)

Guidance literature:

With sodium acetate; acetic acid; for 10h; Reflux;

Reference yield:

2-thioxo-4-thiazolidinone (141-84-4) + 2-(4-benzyloxybenzylidene)-malononitrile (27389-83-9) → (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone (181765-57-1,1055980-80-7)

Guidance literature:

With triethylamine; at 20 ℃;

DOI:10.1016/j.molstruc.2017.07.009

Reference yield:

2-thioxo-4-thiazolidinone (141-84-4) + p-benzyloxybenzaldehyde (4397-53-9) + diethyl ether (60-29-7,927820-24-4) → (Z)-5-(4-benzyloxyphenyl)methylidene-2-thioxo-4-thiazolidinone (181765-57-1,1055980-80-7)

Guidance literature:

With sodium acetate; In acetic acid;

upstream raw materials:

2-thioxo-4-thiazolidinone

p-benzyloxybenzaldehyde

diethyl ether

4-hydroxy-benzaldehyde