ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Base Information

Chemical Name:ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside
CAS No.:351011-51-3
Molecular Formula:C₆₁H₇₀O₁₁S
Molecular Weight:1011.29
Hs Code.:

Synonyms:ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Suppliers and Price of ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

There total 4 articles about ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 3282-30-2
pivaloyl chloride

: 351011-66-0
ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-thio-β-D-mannopyranoside

: 351011-51-3
ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Guidance literature:: ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-thio-β-D-mannopyranoside; With dmap; In dichloromethane; for 0.5h;

pivaloyl chloride; at 20 ℃; for 1h; Further stages.;
DOI:10.1021/jo015521z

Reference yield:

: 114117-12-3
2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-1,5-anhydro-2-deoxy-3,6-di-O-benzyl-D-arabino-hex-1-enitol

: 351011-51-3
ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Guidance literature:: Multi-step reaction with 4 steps

1.1: 2,2'-dimethyldioxirane / CH₂Cl₂; acetone / 0.17 h / 0 °C

2.1: 143 mg / trifluoroacetic anhydride / CH₂Cl₂ / 16 h / -78 - 20 °C

3.1: Ac₂O; DMSO / 72 h / 20 °C

3.2: 47 percent / NaBH₄ / CH₂Cl₂; methanol / 2 h / 0 - 20 °C

4.1: DMAP / CH₂Cl₂ / 0.5 h

4.2: 95 percent / 1 h / 20 °C

With dmap; 2,2'-dimethyldioxirane; acetic anhydride; dimethyl sulfoxide; trifluoroacetic anhydride; In dichloromethane; acetone;
DOI:10.1021/jo015521z

Reference yield:

: (3R,4R,5S)-5-Benzyloxy-3-benzyloxymethyl-4-((2S,3R,4S,5S,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-yloxy)-2,7-dioxa-bicyclo[4.1.0]heptane

: 351011-51-3
ethyl 2,3,4,6-tetra-O-benzyl-β-D-galactopyranosyl-(1->4)-3,6-di-O-benzyl-2-O-pivaloyl-thio-β-D-mannopyranoside

Guidance literature:: Multi-step reaction with 3 steps

1.1: 143 mg / trifluoroacetic anhydride / CH₂Cl₂ / 16 h / -78 - 20 °C

2.1: Ac₂O; DMSO / 72 h / 20 °C

2.2: 47 percent / NaBH₄ / CH₂Cl₂; methanol / 2 h / 0 - 20 °C

3.1: DMAP / CH₂Cl₂ / 0.5 h

3.2: 95 percent / 1 h / 20 °C

With dmap; acetic anhydride; dimethyl sulfoxide; trifluoroacetic anhydride; In dichloromethane;
DOI:10.1021/jo015521z