1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

Base Information

Chemical Name:1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose
CAS No.:308279-18-7
Molecular Formula:C₃₅H₄₂O₅Si
Molecular Weight:570.801
Hs Code.:

Synonyms:1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

Suppliers and Price of 1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

There total 1 articles about 1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 75-77-4
chloro-trimethyl-silane

: 262300-84-5
1,2-O-isopropylidene-3-O-(3'-methylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylofuranose

: 308279-18-7
1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

Guidance literature:: 1,2-O-isopropylidene-3-O-(3'-methylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylofuranose; With n-butyllithium; In tetrahydrofuran; hexane; at -30 ℃; for 0.5h;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at -30 - 20 ℃; for 0.75h;
DOI:10.1016/S0957-4166(00)00260-3

Reference yield: 62.0%

: 1189-71-5
isocyanate de chlorosulfonyle

: 308279-18-7
1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

: (4'S)-1,2-O-isopropylidene-3-O-[3'-(1-methylethylidene)-4'-trimethylsilylazetidin-2'-on-4'-yl]-5-O-trityl-α-D-xylofuranose

: 308279-20-1
(4'R)-1,2-O-isopropylidene-3-O-[3'-(1-methylethylidene)-4'-trimethylsilylazetidin-2'-on-4'-yl]-5-O-trityl-α-D-xylofuranose

Guidance literature:: isocyanate de chlorosulfonyle; 1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose; With sodium carbonate; In toluene; at -70 - -30 ℃; for 1.5h;

With sodium bis(2-methoxyethoxy)aluminium dihydride; In toluene; at -70 ℃; for 30h; Title compound not separated from byproducts;
DOI:10.1016/S0957-4166(00)00260-3

Reference yield:

: 308279-18-7
1,2-O-isopropylidene-3-O-(3'-methyl-1'-trimethylsilylbuta-1',2'-dienyl)-5-O-trityl-α-D-xylo-furanose

: (4'R)-3-O-[N-acetyl-3'-(1-methylethylidene)-4'-trimethylsilylazetidin-2'-on-4'-yl]-5-O-trityl-α-D-xylofuranose

Guidance literature:: Multi-step reaction with 2 steps

1.1: Na₂CO₃ / toluene / 1.5 h / -70 - -30 °C

1.2: 62 percent / Red-Al / toluene / 30 h / -70 °C

2.1: 76 percent / DMAP; pyridine / 1 h / 20 °C

With pyridine; dmap; sodium carbonate; In toluene; 1.1: Cycloaddition / 1.2: reductive cleavage / 2.1: Acetylation;
DOI:10.1016/S0957-4166(00)00260-3