3-(Dimethylamino)propanamide

Base Information

• Chemical Name: 3-(Dimethylamino)propanamide
• CAS No.: 20101-88-6
• Molecular Formula: C₅H₁₂N₂O
• Molecular Weight: 116.163
• European Community (EC) Number: 818-247-5
• Nikkaji Number: J27.686C
• Mol file: 20101-88-6.mol

Synonyms:3-(Dimethylamino)propanamide;20101-88-6;Propanamide, 3-(dimethylamino)-;3-(dimethylamino) propanamide;SCHEMBL177426;SCHEMBL25812974;AKOS009086831;CS-0231943;EN300-1259123;Z168912842

Chemical Property of 3-(Dimethylamino)propanamide

Chemical Property:

• XLogP3: -0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 116.094963011
• Heavy Atom Count: 8
• Complexity: 80.5

Purity/Quality:

99% ^*data from raw suppliers

3-(Dimethylamino)propanamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CCC(=O)N

Technology Process of 3-(Dimethylamino)propanamide

There total 3 articles about 3-(Dimethylamino)propanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-amino-3-(dimethylamino)propane (109-55-7) → 3-(N,N-dimethylamino)propylamide (20101-88-6)

Guidance literature:

With triethanolamine; diphenyl-phosphinic acid; In 2,4-dichlorophenoxyacetic acid dimethylamine; butan-1-ol;

Reference yield:

dimethyl amine (124-40-3) + 2-propenamide (79-06-1,12624-24-7,25038-45-3,27754-57-0,33338-03-3,39387-77-4,68247-81-4,9082-06-8,79079-15-5) → 3-(N,N-dimethylamino)propylamide (20101-88-6)

Guidance literature:

With methanol;

DOI:10.1021/ja01144a509

Reference yield:

→ 3-(N,N-dimethylamino)propylamide (20101-88-6)

Guidance literature:

Nach Zitat¹⁴;

upstream raw materials:

dimethyl amine

2-propenamide

1-amino-3-(dimethylamino)propane

Downstream raw materials:

N,N',N'-trimethylenediamine

Trans-6-[2-[4-[3-Dimethylaminopropyl]aminocarbonylphenyl]ethenyl]-1(2H)-phthalazinone