(4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester

Base Information

• Chemical Name: (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester
• CAS No.: 1208224-25-2
• Molecular Formula: C₂₇H₂₄N₂O₅S
• Molecular Weight: 488.564
• Mol file: 1208224-25-2.mol

Synonyms:(4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester

Chemical Property of (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester

There total 1 articles about (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(fluorenylmethoxy)carbonyl chloride (28920-43-6) + (2RS,4R)-2-(4-acetylaminophenyl)-thiazolidine-4-carboxylic acid (849052-66-0) → (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester (1208224-25-2)

Guidance literature:

With triethylamine; In dichloromethane; at 0 ℃; for 0.5h;

DOI:10.1016/j.bmc.2009.12.020

Reference yield:

n-Dodecylamine (124-22-1) + (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester (1208224-25-2) → C39H49N3O4S (1208224-26-3)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 3.5h;

DOI:10.1016/j.bmc.2009.12.020

Reference yield:

hexadecylamine (143-27-1) + (4R)-2-(4-acetylamino-phenyl)-thiazolidine-3,4-dicarboxylic acid 3-(9H-fluoren-9-ylmethyl)ester (1208224-25-2) → C43H57N3O4S (1208224-32-1)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 20 ℃; for 3.5h;

DOI:10.1016/j.bmc.2009.12.020

upstream raw materials:

(fluorenylmethoxy)carbonyl chloride

(2RS,4R)-2-(4-acetylaminophenyl)-thiazolidine-4-carboxylic acid

Downstream raw materials:

C₃₉H₄₉N₃O₄S

C₄₃H₅₇N₃O₄S