diethyl cyclohexane 1,3-dicarboxylate

Base Information

• Chemical Name: diethyl cyclohexane 1,3-dicarboxylate
• CAS No.: 72903-26-5
• Molecular Formula: C₁₂H₂₀O₄
• Molecular Weight: 228.288
• Mol file: 72903-26-5.mol

Synonyms:diethyl cyclohexane 1,3-dicarboxylate

Chemical Property of diethyl cyclohexane 1,3-dicarboxylate

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of diethyl cyclohexane 1,3-dicarboxylate

There total 6 articles about diethyl cyclohexane 1,3-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

ethanol (64-17-5) + cyclohexane-1,3-dicarboxylic acid (3971-31-1) → diethyl cyclohexane 1,3-dicarboxylate (72903-26-5)

Guidance literature:

With sulfuric acid; at 18 - 25 ℃; for 5h; Product distribution / selectivity; Inert atmosphere; Reflux;

Reference yield:

ethyl 3-hydroxy-2-methylenebutanoate (98837-34-4,130196-00-8,19362-99-3) + ethyl acrylate (140-88-5,9003-32-1) → cis-1,3-Cyclohexanedicarboxylic acid diethyl ester (62059-56-7) + diethyl cyclohexane-trans-1,4-dicarboxylate (19145-96-1) + diethyl cyclohexane-trans-1,3-dicarboxylate (62059-56-7,62059-57-8,72903-26-5,127818-62-6) + diethyl cyclohexane-cis-1,4-dicarboxylate

Guidance literature:

ethyl 3-hydroxy-2-methylenebutanoate; ethyl acrylate; With sulfuric acid; hydroquinone; In N,N-dimethyl-formamide; at 150 ℃; for 12h; Sealed tube;

With palladium on activated charcoal; hydrogen; at 20 ℃; for 4h; Flow reactor;

DOI:10.1002/anie.202113471

Reference yield:

2-Ethylhexyl acrylate (103-11-7) + C13H24O3 → diethyl isophthalate (636-53-3) + diethyl cyclohexane 1,3-dicarboxylate (72903-26-5) + cyclohexane-1,4-dicarboxylic acid diethyl ester (72903-27-6) + diethyl terephthalate (636-09-9)

Guidance literature:

2-Ethylhexyl acrylate; C₁₃H₂₄O₃; With sulfuric acid; hydroquinone; In N,N-dimethyl-formamide; at 150 ℃; for 12h; Sealed tube;

With palladium on activated charcoal; at 240 ℃; for 10h; Temperature; Inert atmosphere; Flow reactor;

DOI:10.1002/anie.202113471

upstream raw materials:

ethanol

cyclohexane-1,3-dicarboxylic acid

2-Ethylhexyl acrylate

ethyl iodide

Downstream raw materials:

1-allyl-cyclohexane-1,3-dicarboxylic acid diethyl ester