Technology Process of dimethyl 4-pentadecylbenzylphosphonate
There total 7 articles about dimethyl 4-pentadecylbenzylphosphonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 20 % Pd(OH)2/C; hydrogen / methanol / 2 h / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere
3: phosphorus tribromide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
4: 18 h / Reflux; Inert atmosphere
With
lithium aluminium tetrahydride; 20 % Pd(OH)2/C; hydrogen; phosphorus tribromide;
In
tetrahydrofuran; methanol; dichloromethane;
4: Michaelis-Arbuzov reaction;
DOI:10.1002/cmdc.201000425
- Guidance literature:
-
Multi-step reaction with 2 steps
1: phosphorus tribromide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
2: 18 h / Reflux; Inert atmosphere
With
phosphorus tribromide;
In
dichloromethane;
2: Michaelis-Arbuzov reaction;
DOI:10.1002/cmdc.201000425
- Guidance literature:
-
Multi-step reaction with 5 steps
1: palladium diacetate; triethylamine / N,N-dimethyl-formamide / 16 h / Reflux; Inert atmosphere
2: 20 % Pd(OH)2/C; hydrogen / methanol / 2 h / 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere
4: phosphorus tribromide / dichloromethane / 1 h / 0 - 20 °C / Inert atmosphere
5: 18 h / Reflux; Inert atmosphere
With
lithium aluminium tetrahydride; 20 % Pd(OH)2/C; hydrogen; palladium diacetate; phosphorus tribromide; triethylamine;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
1: Heck reaction / 5: Michaelis-Arbuzov reaction;
DOI:10.1002/cmdc.201000425
