Chemical Property of Chloromethyl methyl sulfide
Chemical Property:
- Appearance/Colour:clear yellow to brown liquid
- Vapor Pressure:35mmHg at 25°C
- Refractive Index:n20/D 1.498(lit.)
- Boiling Point:105 °C at 760 mmHg
- Flash Point:17.2 °C
- PSA：25.30000
- Density:1.111 g/cm3
- LogP:1.54570
- Storage Temp.:2-8°C
- Sensitive.:Moisture Sensitive
- Water Solubility.:Soluble in acetonitrile, ether and dichloromethane. Insoluble in water.
- XLogP3:1.6
- Hydrogen Bond Donor Count:0
- Hydrogen Bond Acceptor Count:1
- Rotatable Bond Count:1
- Exact Mass:95.9800490
- Heavy Atom Count:4
- Complexity:10
- Purity/Quality:
-
97% *data from raw suppliers
Chloromethyl Methyl Sulfide *data from reagent suppliers
Safty Information:
- Pictogram(s):
F,
Xi
- Hazard Codes:F,Xi
- Statements:
11-37
- Safety Statements:
9-16-33
- MSDS Files:
-
SDS file from LookChem
Useful:
- Canonical SMILES:CSCCl
-
Uses
Chloromethyl methyl sulfide is used as a methylene transfer reagent for iron(II) mediated cyclopropanation and for carbonyl and aromatic compounds. It protects alcohols as their methylthiomethyl (MTM) ethers by reaction, e.g. with NaH/NaI in DME. It is also used for the preparation of MTM esters of carboxylic acids, e.g. by treatment of the K salt of the acid in the presence of NaI and 18-crown-6 and for reaction with cyclopentadienyl iron dicarbonyl dimer in the formation of an iron-containing methylene transfer agent. Methylthiomethylating reagent for carbonyl and aromatic compounds. Methylene transfer reagent for iron(II) mediated cyclopropanation.
