3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester

Base Information

• Chemical Name: 3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester
• CAS No.: 191924-73-9
• Molecular Formula: C₁₄H₂₂O₄
• Molecular Weight: 254.326
• Mol file: 191924-73-9.mol

Synonyms:3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester

Chemical Property of 3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester

There total 2 articles about 3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

tert-butyl 3,5-dimethoxybenzoate + methyl iodide (74-88-4) → 3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester (191924-73-9)

Guidance literature:

With ammonia; In tetrahydrofuran; tert-butyl alcohol; at -78 ℃; for 2h;

DOI:10.1021/ja964231a

Reference yield:

potassium tert-butylate (865-47-4) + 3,5-dimethoxybenzoic acid (1132-21-4) + methyl iodide (74-88-4) → 3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester (191924-73-9)

Guidance literature:

potassium tert-butylate; 3,5-dimethoxybenzoic acid; With thionyl chloride;

methyl iodide; With ammonia; potassium;

Reference yield: 86.0%

3,5-Dimethoxy-1-methyl-cyclohexa-2,5-dienecarboxylic acid tert-butyl ester (191924-73-9) → 1-Methyl-3,5-dioxo-cyclohexanecarboxylic acid tert-butyl ester (191924-66-0)

Guidance literature:

With mercury(II) nitrate; In water; acetonitrile; for 12h; Heating;

DOI:10.1021/ja964231a

upstream raw materials:

methyl iodide

potassium tert-butylate

3,5-dimethoxybenzoic acid

Downstream raw materials:

1-Methyl-3,5-dioxo-cyclohexanecarboxylic acid tert-butyl ester

4-(1-Methoxycarbonyl-2-nitro-ethyl)-1-methyl-3,5-dioxo-cyclohexanecarboxylic acid tert-butyl ester

(3,5-dimethoxy-1-methylcyclohexa-2,5-dienyl)methanol