N-prop-2-enylbenzocarbothioamide

Base Information

• Chemical Name: N-prop-2-enylbenzocarbothioamide
• CAS No.: 130012-62-3
• Molecular Formula: C₁₀H₁₁NS
• Molecular Weight: 177.27
• Mol file: 130012-62-3.mol

Synonyms:N-prop-2-enylbenzocarbothioamide

Chemical Property of N-prop-2-enylbenzocarbothioamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-prop-2-enylbenzocarbothioamide

There total 11 articles about N-prop-2-enylbenzocarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

N-allylbenzamide (10283-95-1) → N-prop-2-enylbenzocarbothioamide (130012-62-3)

Guidance literature:

With Lawessons reagent; In tetrahydrofuran; at 80 ℃; for 3h; Inert atmosphere;

DOI:10.1021/acs.orglett.1c01607

Reference yield: 95.0%

dimethyl N-thiobenzoyl-N-allylphosphoramidate (130012-53-2) → N-allylbenzamide (10283-95-1) + N-prop-2-enylbenzocarbothioamide (130012-62-3)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; Ambient temperature;

DOI:10.1021/jo00312a012

Reference yield: 75.0%

N-allylformamide (16250-37-6) + benzaldehyde (100-52-7) → N-prop-2-enylbenzocarbothioamide (130012-62-3)

Guidance literature:

With pyridine; dipotassium peroxodisulfate; sodiumsulfide nonahydrate; In water; at 100 ℃; for 2h; Schlenk technique;

DOI:10.1021/acs.orglett.5b03541

upstream raw materials:

N-allyl isothiocyanate

N-allylbenzamide

dimethyl N-thiobenzoyl-N-allylphosphoramidate

phenylmagnesium iodide

Downstream raw materials:

2-phenyl-5-((phenylselanyl)methyl)-4,5-dihydrothiazole

5-Methyl-2-phenyl-2-thiazoline

N-allylbenzamide