N-Allylformamide

Base Information

• Chemical Name: N-Allylformamide
• CAS No.: 16250-37-6
• Molecular Formula: C4H7NO
• Molecular Weight: 85.1057
• Hs Code.: 2924199090
• Mol file: 16250-37-6.mol

Synonyms:NSC 77938;Formamide,N-2-propenyl- (9CI);Formamide, N-allyl- (6CI,8CI);Allylformamide;

Chemical Property of N-Allylformamide

Chemical Property:

• Vapor Pressure: 0.0979mmHg at 25°C
• Refractive Index: 1.416
• Boiling Point: 223.1 °C at 760 mmHg
• Flash Point: 114.4 °C
• PSA: 29.10000
• Density: 0.888 g/cm³
• LogP: 0.94520

Purity/Quality:

99% ^*data from raw suppliers

N-Allylformamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-Allylformamide

There total 13 articles about N-Allylformamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

1-amino-2-propene (107-11-9,30551-89-4) + formic acid ethyl ester (109-94-4) → N-allylformamide (16250-37-6)

Guidance literature:

at 60 ℃; for 6h;

DOI:10.1002/chem.201805318

Reference yield: 99.0%

N,N-dimethyl-formamide (68-12-2,33513-42-7) + 1-amino-2-propene (107-11-9,30551-89-4) → N-allylformamide (16250-37-6)

Guidance literature:

N,N-dimethyl-formamide; With bis(2-chlorophenyl)borinic acid; acetic acid; at 65 ℃; for 0.25h; Inert atmosphere;

1-amino-2-propene; at 65 ℃; for 24h; Inert atmosphere; Sealed tube;

DOI:10.1002/chem.201600234

Reference yield: 91.0%

allylisocyanate (1476-23-9) → N-allylformamide (16250-37-6)

Guidance literature:

With zirconocene dichloride; lithium tri-t-butoxyaluminum hydride; In tetrahydrofuran; 2-methyltetrahydrofuran; at 0 - 20 ℃; for 1h; chemoselective reaction; Inert atmosphere;

DOI:10.1021/acs.orglett.6b01226

upstream raw materials:

formic acid

N-allyl isothiocyanate

formyl fluoride

1-amino-2-propene

Downstream raw materials:

N-(N'-Phenylformimidoyl)N-allylformamid

C₁₂H₂₀N₂O₃

N-methyl-N-allylamine

N-prop-2-enylbenzocarbothioamide