4-HYDROXYPTERIDINE

Base Information

• Chemical Name: 4-HYDROXYPTERIDINE
• CAS No.: 700-47-0
• Molecular Formula: C6H4 N4 O
• Molecular Weight: 148.124
• Hs Code.: 2933990090
• Mol file: 700-47-0.mol

Synonyms:4(1H)-Pteridinone(9CI); 4-Pteridinol (6CI,7CI); 4-Hydroxypteridine; 4-Oxo-3,4-dihydropteridine;NSC 67308; Pteridin-4-one

Chemical Property of 4-HYDROXYPTERIDINE

Chemical Property:

• Vapor Pressure: 1.46E-05mmHg at 25°C
• Melting Point: >350 °C
• Refractive Index: 1.6900 (estimate)
• Boiling Point: 366.5°C at 760 mmHg
• PKA: pK1:1.3(＋1);pK2:7.89(0) (25°C)
• Flash Point: 175.5°C
• PSA: 71.79000
• Density: 1.68g/cm³
• LogP: 0.12540
• Storage Temp.: 2-8°C
• Water Solubility.: 4.975g/L(20 oC)

Purity/Quality:

97% ^*data from raw suppliers

Pteridin-4-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-HYDROXYPTERIDINE

There total 16 articles about 4-HYDROXYPTERIDINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

methanol (67-56-1) + 3-aminopyrazine-2-carboxamide (32587-10-3) → pteridin-4-one (700-47-0)

Guidance literature:

With iodine; sodium hydroxide; In water; at 20 ℃; for 6h; Electrochemical reaction; Green chemistry;

DOI:10.1039/d1ra02706a

Reference yield: 28.0%

N-Pteridin-4-yl-hydroxylamine (76952-41-5) → pteridin-4-one (700-47-0)

Guidance literature:

With hydrogenchloride; for 0.166667h; Heating;

DOI:10.1016/S0040-4020(01)91861-7

Reference yield: 23.0%

5,6-diamino-4(3H)-pyrimidinone (1672-50-0) + 3-morpholino-1-ethyl-1,2,4-triazinium borofluoride → pteridin-4-one (700-47-0) + C7H16N4O

Guidance literature:

In dichloromethane; at 20 ℃;

DOI:10.1007/BF00663874

upstream raw materials:

pteridine

monoperoxyphthalic acid

3-aminopyrazine-2-carboxamide

orthoformic acid triethyl ester

Downstream raw materials:

3-methyl-3H-pteridin-4-one

4-methoxy-pteridine

3-aminopyrazinoic acid

5,6,7,8-tetrahydropteridin-4(3H)-one