Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate

Base Information

Chemical Name:Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate
CAS No.:23234-32-4
Molecular Formula:C24H30N2O6
Molecular Weight:442.512
Hs Code.:
NSC Number:202372,158222

Synonyms:methyl o-benzyl-n-(tert-butoxycarbonyl)tyrosylglycinate;23234-32-4;methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate;NSC202372;NSC158222;AKOS000588377;AKOS022000294;NSC-158222;NSC-202372;SR-01000492312;SR-01000492312-1;METHYL 2-{3-[4-(BENZYLOXY)PHENYL]-2-{[(TERT-BUTOXY)CARBONYL]AMINO}PROPANAMIDO}ACETATE

Suppliers and Price of Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate

Chemical Property:

Vapor Pressure:5.72E-16mmHg at 25°C
Boiling Point:633.8°Cat760mmHg
Flash Point:337.1°C
Density:1.171g/cm³
XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:12
Exact Mass:442.21038668
Heavy Atom Count:32
Complexity:604

Purity/Quality:: 85.0-99.8% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=C(C=C1)OCC2=CC=CC=C2)C(=O)NCC(=O)OC

Technology Process of Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate

There total 3 articles about Methyl 2-[[2-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylmethoxyphenyl)propanoyl]amino]acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 23234-32-4
N-Boc-Tyr(Bn)-Gly-OMe

Guidance literature:

Reference yield: 88.0%

: 7733-20-2
Boc-L-Tyr-Gly-OMe

: 100-39-0
benzyl bromide

: 23234-32-4
N-Boc-Tyr(Bn)-Gly-OMe

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 64h;
DOI:10.1021/acs.jmedchem.9b01199

Reference yield:

: 3978-80-1
Boc-Tyr-OH

: 23234-32-4
N-Boc-Tyr(Bn)-Gly-OMe

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; benzotriazol-1-ol / N,N-dimethyl-formamide; acetonitrile / 16 h / 0 - 20 °C

2: potassium carbonate / acetone / 64 h / 20 °C

With potassium carbonate; benzotriazol-1-ol; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; triethylamine; In N,N-dimethyl-formamide; acetone; acetonitrile;
DOI:10.1021/acs.jmedchem.9b01199