Ditolamide

Base Information

• Chemical Name: Ditolamide
• CAS No.: 723-42-2
• Molecular Formula: C13H21 N O2 S
• Molecular Weight: 255.381
• Hs Code.: 2935009090
• Mol file: 723-42-2.mol

Synonyms:p-Toluenesulfonamide,N,N-dipropyl- (6CI,7CI,8CI); Ditolamide; N,N-Dipropyl-p-toluenesulfonamide; NSC406152

Chemical Property of Ditolamide

Chemical Property:

• Vapor Pressure: 2.52E-05mmHg at 25°C
• Boiling Point: 358.6°C at 760 mmHg
• Flash Point: 170.7°C
• PSA: 45.76000
• Density: 1.076g/cm³
• LogP: 3.88650

Purity/Quality:

99% ^*data from raw suppliers

4-METHYL-N,N-DIPROPYLBENZENESULFONAMIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Ditolamide is used as plasticizers for imidazolidinetrione derivative polymers e.g. polyiminoimidazolinediones or polyparabanic acids.

Technology Process of Ditolamide

There total 16 articles about Ditolamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

N,N-dipropyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonamide + methyl iodide (74-88-4) → 4-methyl-N,N-dipropylbenzenesulfonamide (723-42-2)

Guidance literature:

With C₂₁H₃₀ClNPPd; potassium tert-butylate; In tert-Amyl alcohol; at 65 ℃; for 18h; Sealed tube; Inert atmosphere; Glovebox;

DOI:10.1021/acs.orglett.9b00025

Reference yield: 93.0%

N-(3-iodopropyl)-4-methyl-N-propylbenzenesulfonamide → 4-methyl-N,N-dipropylbenzenesulfonamide (723-42-2) + N-allyl-N-propyltosylamide

Guidance literature:

With naphthalene; lithium; manganese(ll) chloride; In tetrahydrofuran; at 0 ℃; for 1.5h;

Reference yield: 93.0%

N-(3-iodopropyl)-4-methyl-N-propylbenzenesulfonamide → 4-methyl-N,N-dipropylbenzenesulfonamide (723-42-2)

Guidance literature:

With [Ir(2-phenylpyridine)-2-(4,4’-di-tert-butyl-2,2’-bipyridine)]PF6; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 25 ℃; for 4h; Irradiation;

DOI:10.1002/anie.201203599

upstream raw materials:

toluene-4-sulfonamide

propyl bromide

di-n-propylamine

p-toluenesulfonyl chloride

Refernces

• 1、 Rosien, Michael,T?ben, Iris,Schmidtmann, Marc,Beckhaus, Rüdiger,Doye, Sven. "Titanium-Catalyzed Hydroaminoalkylation of Ethylene". supporting information. p. 2138 - 2142. Retrieved 2020/02/05.
• 2、 -. "Preparation method of sulfonamide compounds". Paragraph 0022. . Retrieved 2018/09/13.