(S)-naphthalen-2-yl(phenyl)methyl pivalate

Base Information

Chemical Name:(S)-naphthalen-2-yl(phenyl)methyl pivalate
CAS No.:1424035-79-9
Molecular Formula:C₂₂H₂₂O₂
Molecular Weight:318.415
Hs Code.:

Synonyms:(S)-naphthalen-2-yl(phenyl)methyl pivalate

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Chemical Property of (S)-naphthalen-2-yl(phenyl)methyl pivalate

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Technology Process of (S)-naphthalen-2-yl(phenyl)methyl pivalate

There total 2 articles about (S)-naphthalen-2-yl(phenyl)methyl pivalate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 3282-30-2
pivaloyl chloride

: 99412-45-0
(S)-naphthalen-2-yl(phenyl)methanol

: 1424035-79-9
(S)-naphthalen-2-yl(phenyl)methyl pivalate

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1021/ja312087x

Reference yield:

: 3282-30-2
pivaloyl chloride

: 99412-45-0
(S)-naphthalen-2-yl(phenyl)methanol

: 1424035-79-9
(S)-naphthalen-2-yl(phenyl)methyl pivalate

: C₂₂H₂₂O₂

Guidance literature:: With dmap; triethylamine; In dichloromethane; at 20 ℃; for 8h; Overall yield = 88 %; Overall yield = 0.334 g; Inert atmosphere;
DOI:10.1021/ja311783k

Reference yield: 60.0%

: 1424035-79-9
(S)-naphthalen-2-yl(phenyl)methyl pivalate

: 213596-33-9
2-(4-methoxyphenyl)-5,5-dimethyl-1,3,2-dioxaborolane

: 1424035-51-7
2-((S)-(4-methoxyphenyl)(phenyl)methyl)naphthalene

Guidance literature:: With bis(1,5-cyclooctadiene)nickel⁽⁰⁾; potassium tert-butylate; N,N'-dimesityl-4,5-dihydro-1H-imidazolium tetrafluoroborate; In tetrahydrofuran; toluene; butan-1-ol; at 20 ℃; for 24h; enantiospecific reaction; Inert atmosphere;
DOI:10.1021/ja311783k