(-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

Base Information

Chemical Name:(-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine
CAS No.:145440-23-9
Molecular Formula:C₂₅H₂₆Cl₂N₄O₃Si
Molecular Weight:529.498
Hs Code.:

Synonyms:(-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

Suppliers and Price of (-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

There total 2 articles about (-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5451-40-1
2,6 dichloropurine

: 145440-23-9
(-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium sulfate / 1,2-dichloro-ethane / 3 h / Heating

2: TMSOTf / 1,2-dichloro-ethane / a) RT, overnight, b) 80 deg C, 2 h

With ammonium sulfate; trimethylsilyl trifluoromethanesulfonate; In 1,2-dichloro-ethane;
DOI:10.1021/jm00053a004

Reference yield:

: 229635-18-1
(2R)-4-acetoxy-2-<<(tert-butyldiphenylsilyl)oxy>methyl>dioxolane

: 75788-35-1
9-Trimethylsilyl-2,6-dichlorpurin

: (+)-(2R,4S)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

: 145440-23-9
(-)-(2R,4R)-9-<2-<<(tert-butyldiphenylsilyl)oxy>methyl>-1,3-dioxolan-4-yl>-2,6-dichloropurine

Guidance literature:: With trimethylsilyl trifluoromethanesulfonate; In 1,2-dichloro-ethane; Yield given. Yields of byproduct given; a) RT, overnight, b) 80 deg C, 2 h;
DOI:10.1021/jm00053a004