methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Base Information

Chemical Name:methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate
CAS No.:1364597-54-5
Molecular Formula:C₁₆H₁₁Cl₂N₃O₃
Molecular Weight:364.188
Hs Code.:

Synonyms:methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Suppliers and Price of methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

There total 6 articles about methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 1364597-50-1
methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-hydroxyacetate

: 1364597-54-5
methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Guidance literature:: With Dess-Martin periodane; In dichloromethane; at 20 ℃; for 1h;

Reference yield:

: 10420-33-4
dimethyl 2-acetylsuccinate

: 1364597-54-5
methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: toluene-4-sulfonic acid / o-xylene / 2 h / Reflux

2.1: trichlorophosphate / 2.5 h / Reflux

3.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / -78 °C

3.2: 2.5 h / -78 °C

4.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C

With potassium hexamethylsilazane; Dess-Martin periodane; trichlorophosphate; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; o-xylene;

Reference yield:

: 208519-09-9
5-(3-chlorophenyl)-1H-pyrazole-3-amine

: 1364597-54-5
methyl 2-(7-chloro-2-(3-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidin-6-yl)-2-oxoacetate

Guidance literature:: Multi-step reaction with 4 steps

1.1: toluene-4-sulfonic acid / o-xylene / 2 h / Reflux

2.1: trichlorophosphate / 2.5 h / Reflux

3.1: potassium hexamethylsilazane / tetrahydrofuran / 1 h / -78 °C

3.2: 2.5 h / -78 °C

4.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C

With potassium hexamethylsilazane; Dess-Martin periodane; trichlorophosphate; toluene-4-sulfonic acid; In tetrahydrofuran; dichloromethane; o-xylene;