2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester

Base Information

• Chemical Name: 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester
• CAS No.: 1308662-07-8
• Molecular Formula: C₁₄H₁₇NO₅S
• Molecular Weight: 311.359

Synonyms:2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester

Chemical Property of 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester

There total 2 articles about 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester (1253789-57-9) + 3-(bromomethyl)benzaldehyde (82072-23-9) + 1,1-dioxoisothiazolidine-3-carboxylic acid methyl ester (409107-64-8) → 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester (1308662-07-8)

Guidance literature:

1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester; 3-(bromomethyl)benzaldehyde; 1,1-dioxoisothiazolidine-3-carboxylic acid methyl ester; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Inert atmosphere;

With hydrogenchloride; ammonium chloride; In dichloromethane; water; pH=~ 2 - 3; Inert atmosphere;

Reference yield: 37.0%

1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester (1253789-57-9) + 3-(bromomethyl)benzaldehyde (82072-23-9) + 1,1-dioxoisothiazolidine-3-carboxylic acid methyl ester (409107-64-8) → 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester (1308662-07-8) + 2-(3-formyl-benzyl)-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid methyl ester (1333145-24-6)

Guidance literature:

With caesium carbonate; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 20h;

Reference yield:

2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester (1308662-07-8) + N-[(2S)-2-amino-3-phenylpropyl]-N,N-dimethylamine (29802-26-4) → 2-{3-[((S)-1-dimethylaminomethyl-2-phenyl-ethylamino)-methyl]-benzyl}-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester (1308662-08-9)

Guidance literature:

With sodium cyanoborohydride; acetic acid; In methanol; at 0 - 20 ℃; for 16h; Inert atmosphere; Cooling with ice;

upstream raw materials:

1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester

3-(bromomethyl)benzaldehyde

1,1-dioxoisothiazolidine-3-carboxylic acid methyl ester

Downstream raw materials:

2-(3-{[(6-Chloro-2-fluoro-3-methoxy-benzyl)-((S)-1 dimethylaminomethyl-3,3-dimethyl-butyl)-amino]-methyl}-benzyl)-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid

2-(3-{[(6-Chloro-2-fluoro-3-methoxy-benzyl)-((S)-1-dimethylaminomethyl-3,3-dimethyl-butyl)-amino]-methyl}-benzyl)-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester

2-{3-[((S)-1-dimethylaminomethyl-2-phenyl-ethylamino)-methyl]-benzyl}-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid ethyl ester

2-{3-[((S)-1-dimethylaminomethyl-2-phenyl-ethylamino)-methyl]-benzyl}-1,1-dioxo-1λ6-isothiazolidine-3-carboxylic acid

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1308662-07-8 2-(3-Formyl-benzyl)-1,1-dioxo-1λ6 isothiazolidine-3-carboxylic acid ethyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send