MS-347b

Base Information

Chemical Name:MS-347b
CAS No.:58450-00-3
Molecular Formula:C16H12O7
Molecular Weight:316.26
Hs Code.:
Mol file:58450-00-3.mol

Synonyms:sydowinin B;2,8-dihydroxy-6-hydroxymethyl-9-oxo-xanthene-1-carboxylic acid methyl ester;2,8-Dihydroxy-6-hydroxymethyl-9-oxo-9H-xanthene-1-carboxylic acid methyl ester;

Suppliers and Price of MS-347b

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of MS-347b

Chemical Property:

Melting Point:220 °C (ethyl acetate)
PSA：117.20000
LogP:1.63630

Purity/Quality:: >95% by HPLC ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of MS-347b

There total 19 articles about MS-347b which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

: 1161743-83-4
graphisin A

: 58450-00-3
sydowinin B

Guidance literature:: With zinc(II) chloride; In water; at 120 ℃; for 0.166667h; Microwave irradiation; Inert atmosphere;
DOI:10.1021/ol301107m

Reference yield: 51.0%

: 67-56-1
methanol

: 1379535-85-9
C₁₅H₉NO₅

: 58450-00-3
sydowinin B

Guidance literature:: With sulfuric acid; at 60 ℃; for 2h; Inert atmosphere;
DOI:10.1021/ol301107m

Reference yield:

: 2-bromo-3,6-bis(methoxymethoxy)benzaldehyde

: 58450-00-3
sydowinin B

Guidance literature:: Multi-step reaction with 10 steps

1.1: sodium tetrahydroborate / methanol / 0.33 h / 0 °C / Inert atmosphere

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 °C / Inert atmosphere

2.2: 0 - 20 °C / Inert atmosphere

3.1: tert.-butyl lithium / diethyl ether; pentane / 0.08 h / -78 °C / Inert atmosphere

3.2: -78 - 20 °C / Inert atmosphere

4.1: 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione / dichloromethane; dimethyl sulfoxide / 3 h / 20 °C / Inert atmosphere

5.1: palladium 10% on activated carbon; hydrogen / tetrahydrofuran; methanol / 8 h / 20 °C / Inert atmosphere

6.1: Dess-Martin periodane / dichloromethane / 1 h / 20 °C / Inert atmosphere

7.1: sodium chlorite; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene / tetrahydrofuran; water; tert-butyl alcohol / 0 - 20 °C / Inert atmosphere

8.1: methanol; hexane / 0.33 h / 0 °C / Inert atmosphere

9.1: toluene-4-sulfonic acid / methanol; water / 3 h / 45 °C / Inert atmosphere

10.1: zinc(II) chloride / water / 0.17 h / 120 °C / Microwave irradiation; Inert atmosphere

With sodium chlorite; sodium tetrahydroborate; sodium dihydrogen phosphate monohydrate; 2-methyl-but-2-ene; palladium 10% on activated carbon; hydrogen; tert.-butyl lithium; sodium hydride; Dess-Martin periodane; toluene-4-sulfonic acid; zinc(II) chloride; 1-hydroxy-3H-benz[d][1,2]iodoxole-1,3-dione; In tetrahydrofuran; methanol; diethyl ether; hexane; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide; mineral oil; tert-butyl alcohol; pentane; 6.1: Dess-Martin oxidation / 7.1: Pinnick oxidation;
DOI:10.1021/ol301107m