2-(3-Fluorophenyl)propanoic acid

Base Information

Chemical Name:2-(3-Fluorophenyl)propanoic acid
CAS No.:65487-32-3
Molecular Formula:C₉H₉FO₂
Molecular Weight:168.168
Hs Code.:
European Community (EC) Number:827-701-1
DSSTox Substance ID:DTXSID30496391
Nikkaji Number:J3.650.866C

Synonyms:2-(3-Fluorophenyl)propanoic acid;65487-32-3;Benzeneacetic acid, 3-fluoro-a-methyl-;SCHEMBL2183822;2-(3-Fluorophenyl)propanoicacid;3-fluoro-2-methylphenylaceticacid;DTXSID30496391;XHPMSYWCKADLPJ-UHFFFAOYSA-N;AKOS008146335;(3-Fluoro-2-methyl-phenyl)-acetic acid;EN300-90542;Z792377330

Suppliers and Price of 2-(3-Fluorophenyl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(3-fluorophenyl)propanoicacid
500mg
$ 330.00

Labseeker
2-(3-fluorophenyl)propanoic acid 95
10g
$ 4760.00

Labseeker
2-(3-fluorophenyl)propanoic acid 95
5g
$ 3117.00

Labseeker
2-(3-fluorophenyl)propanoic acid 95
1g
$ 1550.00

Alichem
2-(3-Fluorophenyl)propanoicacid
5g
$ 195.84

Alichem
2-(3-Fluorophenyl)propanoicacid
10g
$ 313.60

AK Scientific
2-(3-Fluorophenyl)propanoicacid
250mg
$ 264.00

Total 7 raw suppliers

Chemical Property of 2-(3-Fluorophenyl)propanoic acid

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:168.05865769
Heavy Atom Count:12
Complexity:170

Purity/Quality:

97% ^*data from raw suppliers

2-(3-fluorophenyl)propanoicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C1=CC(=CC=C1)F)C(=O)O

Technology Process of 2-(3-Fluorophenyl)propanoic acid

There total 7 articles about 2-(3-Fluorophenyl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1073-06-9
3-fluorobromobenzene

: 56985-74-1
2-bromopropionic acid sodium salt

: 65487-32-3
2-(3-fluorophenyl)propionic acid

Guidance literature:: 3-fluorobromobenzene; With iodine; magnesium; In tetrahydrofuran; at 50 - 60 ℃; for 1h; Inert atmosphere;

2-bromopropionic acid sodium salt; In tetrahydrofuran; at 0 - 10 ℃; for 1h; Concentration; Temperature; Reflux;

Reference yield: 60.0%

: 124-38-9,18923-20-1
carbon dioxide

: 350-51-6
3-fluorostyrene

: 65487-32-3
2-(3-fluorophenyl)propionic acid

Guidance literature:: carbon dioxide; 3-fluorostyrene; With neocuproine; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 24h; under 760.051 Torr; Molecular sieve; Irradiation;

With hydrogenchloride; water; regioselective reaction;
DOI:10.1021/jacs.7b13448

Reference yield:

: 331-25-9
(3-fluorophenyl)acetic acid

: 74-88-4
methyl iodide

: 65487-32-3
2-(3-fluorophenyl)propionic acid

Guidance literature:: (3-fluorophenyl)acetic acid; With n-butyllithium; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; hexanes; at -50 - 20 ℃; for 1h;

methyl iodide; In tetrahydrofuran; hexanes; at 20 ℃; for 18h;