(3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Base Information

Chemical Name:(3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride
CAS No.:1439921-99-9
Molecular Formula:C₈H₁₇NO₂*ClH
Molecular Weight:195.689
Hs Code.:

Synonyms:(3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Suppliers and Price of (3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(S)-Methyl3-Amino-4,4-dimethylpentanateHydrochloride
10mg
$ 45.00

Crysdot
(S)-Methyl3-amino-4,4-dimethylpentanoatehydrochloride 95+%
5g
$ 1719.00

Crysdot
(S)-Methyl3-amino-4,4-dimethylpentanoatehydrochloride 95+%
1g
$ 490.00

Chemenu
(S)-Methyl3-amino-4,4-dimethylpentanoatehydrochloride 95%
1g
$ 463.00

AK Scientific
(S)-Methyl3-amino-4,4-dimethylpentanoatehydrochloride
1g
$ 534.00

AK Scientific
(S)-Methyl3-amino-4,4-dimethylpentanoatehydrochloride
250mg
$ 258.00

Total 3 raw suppliers

Chemical Property of (3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Chemical Property:

Purity/Quality:

97% ^*data from raw suppliers

(S)-Methyl3-Amino-4,4-dimethylpentanateHydrochloride ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

There total 5 articles about (3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.9%

: 67-56-1
methanol

: 367278-48-6
(S)‐3‐amino‐4,4‐dimethylpentanoic acid

: 1439921-99-9
(3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Guidance literature:: With thionyl chloride; at 0 - 65 ℃; for 2h;

Reference yield:

: C₁₁H₂₃NO₄S

: 1439921-99-9
(3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluorormethanesulfonic acid / dichloromethane / 60 h / 0 °C / Inert atmosphere

1.2: Dowex 50WX₈-200, hydrogen form / 0 °C / Inert atmosphere

2.1: thionyl chloride / 16 h / 0 - 20 °C / Inert atmosphere

With thionyl chloride; trifluorormethanesulfonic acid; In dichloromethane;
DOI:10.1021/jacs.7b08496

Reference yield:

: 630-19-3
pivalaldehyde

: 1439921-99-9
(3S)-3-amino-4,4-dimethyl-pentanoic acid methyl ester hydrochloride

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridinium p-toluenesulfonate; magnesium sulfate / dichloromethane / 48 h / 20 °C / Inert atmosphere

2.1: dichloromethane; diethyl ether / 20 h / -41 - 10 °C / Inert atmosphere

3.1: sodium periodate; ruthenium(III) trichloride hydrate / water; tetrachloromethane; acetonitrile / 16 h / 20 °C / Inert atmosphere

4.1: trifluorormethanesulfonic acid / dichloromethane / 60 h / 0 °C / Inert atmosphere

4.2: Dowex 50WX₈-200, hydrogen form / 0 °C / Inert atmosphere

5.1: thionyl chloride / 16 h / 0 - 20 °C / Inert atmosphere

With sodium periodate; thionyl chloride; trifluorormethanesulfonic acid; ruthenium(III) trichloride hydrate; pyridinium p-toluenesulfonate; magnesium sulfate; In tetrachloromethane; diethyl ether; dichloromethane; water; acetonitrile;
DOI:10.1021/jacs.7b08496