2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine

Base Information

• Chemical Name: 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine
• CAS No.: 112321-79-6
• Molecular Formula: C₂₃H₁₇N
• Molecular Weight: 307.395
• Mol file: 112321-79-6.mol

Synonyms:2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine

Chemical Property of 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine

There total 14 articles about 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

5-oxo-5-phenylpentanenitrile (10413-00-0) + 4-biphenylboronic acid (5122-94-1) → 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine (112321-79-6)

Guidance literature:

With [2,2]bipyridinyl; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; trifluoroacetic acid; In methanol; at 90 ℃; for 12h; Sealed tube;

DOI:10.1021/acscombsci.9b00198

Reference yield: 81.0%

1-(4-phenyl-phenyl)-1-ethanol (3562-73-0) + 3-amino-3-phenyl-1-propanol (14593-04-5,82769-76-4) → 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine (112321-79-6)

Guidance literature:

With C₁₅H₁₅Cl₃N₅Ru; potassium tert-butylate; In toluene; at 110 ℃; for 24h; Inert atmosphere; Schlenk technique;

DOI:10.1002/cctc.201900435

Reference yield: 71.0%

2-phenylpyridin N-oxide (1131-33-5) + 2-([1,1'-biphenyl]-4-yl)-5,5-dimethyl-1,3,2-dioxaborinane (5123-05-7) → 2-([1,1'-biphenyl]-4-yl)-6-phenylpyridine (112321-79-6)

Guidance literature:

With copper acetylacetonate; potassium tert-butylate; oxygen; In toluene; at 110 ℃; for 2h;

DOI:10.1039/c3cc48767a

upstream raw materials:

2-(4-phenylphenyl)pyridine

phenyllithium

1-([1,1'-biphenyl]-4-yl)-5-phenylpentane-1,5-dione

dithiocarbonic acid S-[1-benzoyl-4-(biphenyl-4-yl)-4-oxobutyl] ester O-ethyl ester