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2-bromo-5-triethylsilylpyridine

Base Information Edit
  • Chemical Name:2-bromo-5-triethylsilylpyridine
  • CAS No.:1012314-95-2
  • Molecular Formula:C11H18BrNSi
  • Molecular Weight:272.26
  • Hs Code.:
  • Mol file:1012314-95-2.mol
2-bromo-5-triethylsilylpyridine

Synonyms:2-bromo-5-(triethylsilyl)pyridine

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The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of 2-bromo-5-triethylsilylpyridine Edit
Chemical Property:
  • Boiling Point:302.5±22.0 °C(Predicted) 
  • PKA:1.06±0.10(Predicted) 
  • Density:1.18±0.1 g/cm3(Predicted) 
Purity/Quality:
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Technology Process of 2-bromo-5-triethylsilylpyridine

There total 2 articles about 2-bromo-5-triethylsilylpyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
2,5-dibromopyridine; With n-butyllithium; In tetrahydrofuran; hexane; at -100 ℃; for 0.5h;
triethylsilyl chloride; In tetrahydrofuran; hexane; at 0 ℃; for 0.5h; Further stages.;
DOI:10.1039/b715442a
Guidance literature:
With n-butyllithium; In diethyl ether; hexane; at -78 ℃; for 2h;
In diethyl ether; hexane; at -78 - 20 ℃; for 17h;
Guidance literature:
In neat (no solvent); at 170 ℃; for 40h; Sealed tube;
DOI:10.1002/anie.202009335
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