methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Base Information

Chemical Name:methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate
CAS No.:190203-16-8
Molecular Formula:C₂₆H₄₀N₄O₉
Molecular Weight:552.625
Hs Code.:

methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Synonyms:methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Suppliers and Price of methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

There total 7 articles about methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 67-56-1
methanol

: 190203-15-7
1,1,1-tris(methylthio)-3(S)-[(phenylmethoxycarbonyl)amino]-6-({[(tert-butyloxycarbonyl)imino][(tert-butyloxycarbonyl)amino]methyl}amino)hexan-2(R,S)-ol

: 190203-16-8
methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Guidance literature:: With mercury dichloride; mercury(II) oxide; In water; for 72h; Ambient temperature;
DOI:10.1021/jo961447m

Reference yield:

: 70-26-8,25104-12-5,410523-47-6
L-ornithine

: 190203-16-8
methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) CuCO₃, 2.) DIPEA, 3.) EDTA, NaHCO₃ / 1.) H₂O, 100 deg C, 1 h, 2.) formamide, room temperature, 24 h, 3.) acetone, H₂O, room temperature, 12 h

2: 91 percent / CH₂Cl₂; ethanol / 0 °C

3: 97 percent / DIBALH / CH₂Cl₂; hexane / 1.25 h / -65 °C

4: 53.6 percent / n-BuLi / hexane; tetrahydrofuran / 5 h / -65 °C / 1.) 20 min, 2.) 5 h

5: 79 percent / HgCl₂, HgO / H₂O / 72 h / Ambient temperature

With copper(II) carbonate; n-butyllithium; ethylenediaminetetraacetic acid; diisobutylaluminium hydride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; mercury dichloride; mercury(II) oxide; In tetrahydrofuran; ethanol; hexane; dichloromethane; water;
DOI:10.1021/jo961447m

Reference yield:

: 501-53-1,94274-21-2
benzyl chloroformate

: 190203-16-8
methyl 2(R,S)-hydroxy-3(S)-<(phenylmethoxycarbonyl)amino>-6-<<<(tert-butyloxycarbonyl)imino><(tert-butyloxycarbonyl)amino>methyl>amino>hexanoate

Guidance literature:: Multi-step reaction with 5 steps

1: 1.) CuCO₃, 2.) DIPEA, 3.) EDTA, NaHCO₃ / 1.) H₂O, 100 deg C, 1 h, 2.) formamide, room temperature, 24 h, 3.) acetone, H₂O, room temperature, 12 h

2: 91 percent / CH₂Cl₂; ethanol / 0 °C

3: 97 percent / DIBALH / CH₂Cl₂; hexane / 1.25 h / -65 °C

4: 53.6 percent / n-BuLi / hexane; tetrahydrofuran / 5 h / -65 °C / 1.) 20 min, 2.) 5 h

5: 79 percent / HgCl₂, HgO / H₂O / 72 h / Ambient temperature

With copper(II) carbonate; n-butyllithium; ethylenediaminetetraacetic acid; diisobutylaluminium hydride; sodium hydrogencarbonate; N-ethyl-N,N-diisopropylamine; mercury dichloride; mercury(II) oxide; In tetrahydrofuran; ethanol; hexane; dichloromethane; water;
DOI:10.1021/jo961447m