3-chloro-2-phenyl quinoline

Base Information

• Chemical Name: 3-chloro-2-phenyl quinoline
• CAS No.: 59280-67-0
• Molecular Formula: C₁₅H₁₀ClN
• Molecular Weight: 239.704

Synonyms:3-chloro-2-phenyl quinoline

Chemical Property of 3-chloro-2-phenyl quinoline

Chemical Property:

Purity/Quality:

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Technology Process of 3-chloro-2-phenyl quinoline

There total 10 articles about 3-chloro-2-phenyl quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

2-phenyl-indole (948-65-2) + chloroform (67-66-3,8013-54-5) → 3-chloro-2-phenyl quinoline (59280-67-0)

Guidance literature:

With potassium hydroxide; tetra(n-butyl)ammonium hydrogensulfate; for 6h; Ambient temperature;

Reference yield:

2-phenyl-indole (948-65-2) + chloroform (67-66-3,8013-54-5) → 2-phenyl-1H-indol-3-carboxaldehyde (25365-71-3) + 3-chloro-2-phenyl quinoline (59280-67-0)

Guidance literature:

With potassium hydroxide; ethanol; water;

DOI:10.1021/jo01179a016

Reference yield:

2-phenyl-indole (948-65-2) + ethanol (64-17-5) + chloroform (67-66-3,8013-54-5) → 2-phenyl-1H-indol-3-carboxaldehyde (25365-71-3) + 3-chloro-2-phenyl quinoline (59280-67-0)

Guidance literature:

DOI:10.1021/jo01179a016

upstream raw materials:

2-phenyl-indole

chloroform

2-phenyl-quinolin-3-ylamine

ethanol

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