(4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Base Information

• Chemical Name: (4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine
• CAS No.: 1335150-79-2
• Molecular Formula: C₄₉H₆₇OP
• Molecular Weight: 703.044
• Mol file: 1335150-79-2.mol

Synonyms:(4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Chemical Property of (4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

There total 1 articles about (4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (958007-24-4) + benzonitrile (100-47-0) → (4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (1335150-79-2)

Guidance literature:

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

benzonitrile; In tetrahydrofuran; hexane; at 20 ℃; Inert atmosphere;

With hydrogenchloride; water; In tetrahydrofuran; hexane; Inert atmosphere;

DOI:10.1016/j.jorganchem.2011.07.013

Reference yield: 79.0%

2,6-Di-tert-butyl-4-iodophenol (40084-31-9) + (4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (1335150-79-2) → [4-{bis(2,4,6-triisopropylphenyl)phosphino}-3,5-diisopropylphenyl](3,5-di-tert-butyl-4-hydroxyphenyl)phenylmethanol (1335150-82-7)

Guidance literature:

2,6-Di-tert-butyl-4-iodophenol; With n-butyllithium; In diethyl ether; hexane; at -78 - 20 ℃; Inert atmosphere;

(4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine; In diethyl ether; hexane; at -78 - 20 ℃; Inert atmosphere;

With water; ammonium chloride; In diethyl ether; hexane; Inert atmosphere;

DOI:10.1016/j.jorganchem.2011.07.013

Reference yield:

(4-benzoyl-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine (1335150-79-2) → 4-[[4-{bis(2,4,6-triisopropylphenyl)phosphino}-3,5-diisopropylphenyl](phenyl)methylene]-2,6-di-tert-butyl-2,5-cyclohexadiene-1-one (1335150-80-5)

Guidance literature:

Multi-step reaction with 2 steps

1.1: n-butyllithium / diethyl ether; hexane / -78 - 20 °C / Inert atmosphere

1.2: -78 - 20 °C / Inert atmosphere

1.3: Inert atmosphere

2.1: trifluoroacetic acid / benzene / 0.08 h / Inert atmosphere

2.2: 0.08 h / Inert atmosphere

With n-butyllithium; trifluoroacetic acid; In diethyl ether; hexane; benzene;

DOI:10.1016/j.jorganchem.2011.07.013

upstream raw materials:

(4-bromo-2,6-diisopropylphenyl)bis(2,4,6-triisopropylphenyl)phosphine

benzonitrile

Downstream raw materials:

4-[[4-{bis(2,4,6-triisopropylphenyl)phosphino}-3,5-diisopropylphenyl](phenyl)methylene]-2,6-di-tert-butyl-2,5-cyclohexadiene-1-one

[4-{bis(2,4,6-triisopropylphenyl)phosphino}-3,5-diisopropylphenyl](3,5-di-tert-butyl-4-hydroxyphenyl)phenylmethanol