(R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Base Information

Chemical Name:(R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one
CAS No.:1278519-67-7
Molecular Formula:C₂₃H₂₆O₄
Molecular Weight:366.457
Hs Code.:

Synonyms:(R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Suppliers and Price of (R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

There total 8 articles about (R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

: 1313389-76-2
C₂₂H₂₄O₅

: 1779-49-3
Methyltriphenylphosphonium bromide

: 1278519-67-7
(R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Guidance literature:: Methyltriphenylphosphonium bromide; With potassium tert-butylate; In diethyl ether; at 0 - 20 ℃;

C₂₂H₂₄O₅; In diethyl ether; at 0 - 20 ℃;
DOI:10.1021/ol200331u

Reference yield:

: 1278519-66-6
(R)-3-((S)-1-hydroxybutan-3-yl)-8-(4-methoxybenzyloxy)-7-methylisochroman-1-one

: 1278519-67-7
(R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Guidance literature:: Multi-step reaction with 2 steps

1.1: Dess-Martin periodane / dichloromethane / 0 - 20 °C

2.1: potassium tert-butylate / diethyl ether / 0 - 20 °C

2.2: 0 - 20 °C

With potassium tert-butylate; Dess-Martin periodane; In diethyl ether; dichloromethane; 2.2: Wittig reaction;
DOI:10.1021/ol200331u

Reference yield:

: 1278519-63-3
(R)-3-((S)-but-1-en-3-yl)-7-methyl-8-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)isochroman-1-one

: 1278519-67-7
(R)-8-(4-methoxybenzyloxy)-7-methyl-3-((S)-pent-1-en-4-yl)isochroman-1-one

Guidance literature:: Multi-step reaction with 6 steps

1.1: dihydrogen peroxide; sodium hydroxide / tetrahydrofuran; water / 2 h

2.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0.17 h / 0 °C

2.2: 24 h / 55 °C

3.1: Wilkinson's catalyst / tetrahydrofuran / 0.17 h

3.2: 22 h / 20 °C

4.1: dihydrogen peroxide; sodium hydroxide / water / 0.5 h / 0 °C

5.1: Dess-Martin periodane / dichloromethane / 0 - 20 °C

6.1: potassium tert-butylate / diethyl ether / 0 - 20 °C

6.2: 0 - 20 °C

With Wilkinson's catalyst; potassium tert-butylate; dihydrogen peroxide; sodium hydride; Dess-Martin periodane; sodium hydroxide; In tetrahydrofuran; diethyl ether; dichloromethane; water; N,N-dimethyl-formamide; mineral oil; 6.2: Wittig reaction;
DOI:10.1021/ol200331u