3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Base Information

Chemical Name:3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester
CAS No.:1052714-18-7
Molecular Formula:C₁₃H₉F₃N₂O₂
Molecular Weight:282.222
Hs Code.:

Synonyms:3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Suppliers and Price of 3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

There total 6 articles about 3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1052714-13-2
3-amino-6-bromo-5-fluoropyridine-2-carboxylic acid methyl ester

: 162101-25-9
2,6-difluorophenylboronic acid

: 1052714-18-7
3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Guidance literature:: With potassium fluoride; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; tri-tert-butyl phosphine; In tetrahydrofuran; water; toluene; at 90 ℃; for 1.5h; Microwave irradiation;
DOI:10.1021/ml400307j

Reference yield: 94.0%

: 1052714-18-7
3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Guidance literature:

Reference yield: 74.0%

: 863868-37-5
2-(2,6-difluorophenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane

: 1052714-13-2
3-amino-6-bromo-5-fluoropyridine-2-carboxylic acid methyl ester

: 1052714-18-7
3-amino-6-(2,6-difluorophenyl)-5-fluoro-2-pyridinecarboxylicacidmethylester

Guidance literature:: With bis(tri-t-butylphosphine)palladium⁽⁰⁾; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; water; at 100 ℃; for 2h; Inert atmosphere; Sealed tube;