methyl 3-amino-6-bromo-5-fluoropicolinate

Base Information

Chemical Name:methyl 3-amino-6-bromo-5-fluoropicolinate
CAS No.:1052714-13-2
Molecular Formula:C7H6BrFN2O2
Molecular Weight:249.039
Hs Code.:

Synonyms:methyl 3-amino-6-bromo-5-fluoropicolinate

Suppliers and Price of methyl 3-amino-6-bromo-5-fluoropicolinate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
Methyl3-amino-6-bromo-5-fluoropicolinate 95+%
1g
$ 1469.00

Chemcia Scientific
3-Amino-6-bromo-5-fluoro-pyridine-2-carboxylicacidmethylester ＞95%
0.25 G
$ 325.00

Chemcia Scientific
3-Amino-6-bromo-5-fluoro-pyridine-2-carboxylicacidmethylester ＞95%
2.5 G
$ 1450.00

Alichem
Methyl3-amino-6-bromo-5-fluoropicolinate
1g
$ 998.00

Total 4 raw suppliers

Chemical Property of methyl 3-amino-6-bromo-5-fluoropicolinate

Chemical Property:

Boiling Point:340.5±37.0 °C(Predicted)
PSA：65.21000
Density:1.738±0.06 g/cm3(Predicted)
LogP:1.93320

Purity/Quality:

98% ^*data from raw suppliers

Methyl3-amino-6-bromo-5-fluoropicolinate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of methyl 3-amino-6-bromo-5-fluoropicolinate

There total 3 articles about methyl 3-amino-6-bromo-5-fluoropicolinate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1052714-11-0
3-amino-5-fluoropyridine-2-carboxylic acid methyl ester

: 1052714-13-2
3-amino-6-bromo-5-fluoropyridine-2-carboxylic acid methyl ester

Guidance literature:: With N-Bromosuccinimide; In acetonitrile; at 20 ℃; for 2h;

Reference yield:

: 884495-03-8
3-amino-2-bromo-5-fluoropyridine

: 1052714-13-2
3-amino-6-bromo-5-fluoropyridine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloro[2,2′ -bis(diphenylphosphino)-1,1′ -binaphthyl]palladium(II) / 6 h / 100 °C / 3102.97 Torr / Inert atmosphere; Sealed tube

2: N-Bromosuccinimide / acetonitrile / 2 h / 20 °C

With N-Bromosuccinimide; triethylamine; dichloro[2,2′ -bis(diphenylphosphino)-1,1′ -binaphthyl]palladium(II); In acetonitrile;

Reference yield:

: 1033202-51-5
5-fluoro-3-nitropyridine-2-carbonitrile

: 1052714-13-2
3-amino-6-bromo-5-fluoropyridine-2-carboxylic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: tin(ll) chloride / ethanol / 2 h / 90 °C

1.2: 6 h / Reflux

1.3: 24 h / 90 °C

2.1: N-Bromosuccinimide / acetonitrile / 2 h / 20 - 30 °C

With N-Bromosuccinimide; tin(ll) chloride; In ethanol; acetonitrile;