tert-butyl (1-(4-methoxyphenyl)allyl) carbonate

Base Information

• Chemical Name: tert-butyl (1-(4-methoxyphenyl)allyl) carbonate
• CAS No.: 864952-99-8
• Molecular Formula: C₁₅H₂₀O₄
• Molecular Weight: 264.321
• Mol file: 864952-99-8.mol

Synonyms:tert-butyl (1-(4-methoxyphenyl)allyl) carbonate

Chemical Property of tert-butyl (1-(4-methoxyphenyl)allyl) carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl (1-(4-methoxyphenyl)allyl) carbonate

There total 3 articles about tert-butyl (1-(4-methoxyphenyl)allyl) carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + 1-(4-methoxylphenyl)-2-propen-1-ol (51410-44-7) → tert-butyl (1-(4-methoxyphenyl)allyl) carbonate (864952-99-8)

Guidance literature:

1-(4-methoxylphenyl)-2-propen-1-ol; With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.5h;

di-tert-butyl dicarbonate; In tetrahydrofuran; at 20 ℃;

DOI:10.1021/jacs.6b11205

Reference yield:

4-methoxy-benzaldehyde (123-11-5) → tert-butyl (1-(4-methoxyphenyl)allyl) carbonate (864952-99-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: tetrahydrofuran / 0 - 20 °C

2.1: n-butyllithium / tetrahydrofuran / 0.5 h / 0 °C

2.2: 20 °C

With n-butyllithium; In tetrahydrofuran;

DOI:10.1021/jacs.6b11205

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) + vinyl magnesium bromide (1826-67-1) + 4-methoxy-benzaldehyde (123-11-5) → tert-butyl (1-(4-methoxyphenyl)allyl) carbonate (864952-99-8)

Guidance literature:

vinyl magnesium bromide; 4-methoxy-benzaldehyde; In tetrahydrofuran; at 0 ℃; for 2h; Inert atmosphere;

di-tert-butyl dicarbonate; In tetrahydrofuran; for 12h; Inert atmosphere;

DOI:10.1002/anie.201805476

upstream raw materials:

di-tert-butyl dicarbonate

1-(4-methoxylphenyl)-2-propen-1-ol

4-methoxy-benzaldehyde

vinyl magnesium bromide

Downstream raw materials:

[Ru(1-(CH₂CH(C₆H₄OMe)CH=CH₂)-2,3,4,5-tetramethylcyclopentadiene)(4,4'-dimethyl-2,2'-dipyridyl)]PF₆