N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide

Base Information

Chemical Name:N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide
CAS No.:884305-72-0
Molecular Formula:C₁₉H₂₀F₃N₃O₄S
Molecular Weight:443.447
Hs Code.:

Synonyms:N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide

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Technology Process of N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide

There total 1 articles about N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 56.0%

: 884306-56-3
[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-carbamic acid benzyl ester

: 79-03-8
propionyl chloride

: N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-7-yl]-propionamide

: 884305-72-0
N-[3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-propionamide

Guidance literature:: [3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-5-yl]-carbamic acid benzyl ester; [3-(4-trifluoromethoxy-benzenesulfonylamino)-5,6,7,8-tetrahydro-quinolin-7-yl]-carbamic acid benzyl ester; With hydrogen; palladium 10% on activated carbon; In methanol; at 20 ℃; for 3h; under 760.051 Torr;

propionyl chloride; With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 2h;