3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile

Base Information Edit

Chemical Name:3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile
CAS No.:1432048-71-9
Molecular Formula:C₁₂H₁₀F₃NO₂
Molecular Weight:257.212
Hs Code.:
Mol file:1432048-71-9.mol

Synonyms:3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile

Suppliers and Price of 3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile Edit

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile

There total 2 articles about 3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 49561-96-8
(4-trifluoromethoxy-phenyl)-acetonitrile

: 3132-64-7,82584-73-4
1,2-Epoxy-3-bromopropane

: 1432048-71-9
3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile

Guidance literature:: (4-trifluoromethoxy-phenyl)-acetonitrile; With methyllithium; In tetrahydrofuran; diethyl ether; at -75 ℃; for 1h;

1,2-Epoxy-3-bromopropane; In tetrahydrofuran; diethyl ether; at -75 ℃; for 1h;

With methylmagnesium bromide; In tetrahydrofuran; diethyl ether; at 20 ℃;

Reference yield: 100.0%

: 49561-96-8
(4-trifluoromethoxy-phenyl)-acetonitrile

: 917-54-4
methyllithium

: 3132-64-7,82584-73-4
1,2-Epoxy-3-bromopropane

: 1432048-71-9
3-hydroxy-1-[4-(trifluoromethoxy)phenyl]cyclobutanecarbonitrile

Guidance literature:: (4-trifluoromethoxy-phenyl)-acetonitrile; methyllithium; In tetrahydrofuran; diethyl ether; at -75 ℃; for 1h;

1,2-Epoxy-3-bromopropane; In tetrahydrofuran; diethyl ether; at -75 ℃; for 1h;

With hydrogenchloride; methylmagnesium bromide; In tetrahydrofuran; diethyl ether; water; at 20 ℃;