2-Cinnamoylbenzimidazole

Base Information

Chemical Name:2-Cinnamoylbenzimidazole
CAS No.:20224-10-6
Molecular Formula:C16H12N2O
Molecular Weight:248.284
Hs Code.:2933990090
Nikkaji Number:J2.198.699B
Wikidata:Q76387190
ChEMBL ID:CHEMBL2269120
Mol file:20224-10-6.mol

Synonyms:2-Cinnamoylbenzimidazole;20224-10-6;1-(1H-Benzimidazol-2-yl)-3-phenyl-2-propen-1-one;2-Propen-1-one, 1-(1H-benzimidazol-2-yl)-3-phenyl-;(E)-1-(1H-benzimidazol-2-yl)-3-phenylprop-2-en-1-one;2-Propen-1-one, 1-(2-benzimidazolyl)-3-phenyl-;2-Cinnamoyl-1H-benzoimidazole;CHEMBL2269120;AKOS002680579;LS-123813;(2e)-1-(1h-benzimidazol-2-yl)-3-phenylprop-2-en-1-one

Suppliers and Price of 2-Cinnamoylbenzimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CINNAMOYLBENZIMIDAZOLE 95.00%
5MG
$ 502.05

Total 5 raw suppliers

Chemical Property of 2-Cinnamoylbenzimidazole

Chemical Property:

Vapor Pressure:1.19E-09mmHg at 25°C
Melting Point:201-205 °C
Boiling Point:487.4°C at 760 mmHg
PKA:10.30±0.10(Predicted)
Flash Point:245.8°C
PSA：45.75000
Density:1.27g/cm³
LogP:3.45900
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:248.094963011
Heavy Atom Count:19
Complexity:347

Purity/Quality:

99% ^*data from raw suppliers

2-CINNAMOYLBENZIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C=CC(=O)C2=NC3=CC=CC=C3N2
Isomeric SMILES:C1=CC=C(C=C1)/C=C/C(=O)C2=NC3=CC=CC=C3N2

Technology Process of 2-Cinnamoylbenzimidazole

There total 6 articles about 2-Cinnamoylbenzimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 100-52-7
benzaldehyde

: 939-70-8
2-acetylbenzimidazole

: 20224-10-6
1-(1H-benzo[d]imidazol-2-yl)-3-phenylprop-2-en-1-one

Guidance literature:: With sodium hydroxide; at 20 ℃; for 0.166667h;

Reference yield: 70.0%

: (1H-benzimidazol-2-yl)ethan-1-one

: 123-11-5
4-methoxy-benzaldehyde

: 20224-10-6
1-(1H-benzo[d]imidazol-2-yl)-3-phenylprop-2-en-1-one

Guidance literature:: With sodium hydroxide; In ethanol; at 40 ℃; for 0.833333h;
DOI:10.1016/j.bmcl.2021.128210

Reference yield:

: 16414-04-3,19018-24-7
1-benzimidazol-2-ylethanol

: 20224-10-6
1-(1H-benzo[d]imidazol-2-yl)-3-phenylprop-2-en-1-one

Guidance literature:: Multi-step reaction with 2 steps

1: 91 percent / KMnO₄ on neutral alumina / 0.12 h / 20 °C

2: 87 percent / NaOH / 0.17 h / 20 °C

With sodium hydroxide; KMnO₄/alumina;