4-amino-2-methyl-4'-nitrodiphenyl sulfide

Base Information

• Chemical Name: 4-amino-2-methyl-4'-nitrodiphenyl sulfide
• CAS No.: 176512-31-5
• Molecular Formula: C₂₃H₂₃BrN₂O₄S₂
• Molecular Weight: 535.483
• Mol file: 176512-31-5.mol

Synonyms:4-amino-2-methyl-4'-nitrodiphenyl sulfide

Chemical Property of 4-amino-2-methyl-4'-nitrodiphenyl sulfide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-amino-2-methyl-4'-nitrodiphenyl sulfide

There total 3 articles about 4-amino-2-methyl-4'-nitrodiphenyl sulfide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

1,3-dibromo-propane (109-64-8) + 4-Methyl-N-[3-methyl-4-(4-nitro-phenylsulfanyl)-phenyl]-benzenesulfonamide (176512-26-8) → 4-amino-2-methyl-4'-nitrodiphenyl sulfide (176512-31-5)

Guidance literature:

With potassium hydroxide; copper(l) iodide; sodium iodide; In ethanol; Heating;

DOI:10.1002/ardp.19963290309

Reference yield:

3-methyl-4-(4-nitrophenylthio)aniline (176512-23-5) → 4-amino-2-methyl-4'-nitrodiphenyl sulfide (176512-31-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 3 h

2: 74 percent / NaI, CuI, aq. KOH / ethanol / Heating

With potassium hydroxide; copper(l) iodide; sodium iodide; In pyridine; ethanol;

DOI:10.1002/ardp.19963290309

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 4-amino-2-methyl-4'-nitrodiphenyl sulfide (176512-31-5)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine / 3 h

2: 74 percent / NaI, CuI, aq. KOH / ethanol / Heating

With potassium hydroxide; copper(l) iodide; sodium iodide; In pyridine; ethanol;

DOI:10.1002/ardp.19963290309

upstream raw materials:

1,3-dibromo-propane

4-Methyl-N-[3-methyl-4-(4-nitro-phenylsulfanyl)-phenyl]-benzenesulfonamide

3-methyl-4-(4-nitrophenylthio)aniline

p-toluenesulfonyl chloride

Downstream raw materials:

2,4-diamino-5-<3,5-dimethoxy-4-<3-(3'-methyl-4'-(4''-nitrophenyl)sulfonylanilino)propoxy>benzyl>pyrimidine

(3-Bromo-propyl)-[3-methyl-4-(4-nitro-benzenesulfonyl)-phenyl]-amine

N-(3-Bromo-propyl)-4-methyl-N-[3-methyl-4-(4-nitro-benzenesulfonyl)-phenyl]-benzenesulfonamide