(1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Base Information

Chemical Name:(1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide
CAS No.:201553-44-8
Molecular Formula:C₂₃H₂₈N₂O₄
Molecular Weight:396.486
Hs Code.:

Synonyms:(1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Suppliers and Price of (1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

There total 5 articles about (1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 35373-92-3
L-phenylalanine methylamide

: 201553-42-6
(1R,5S,6S)-6-Benzyloxymethyl-3-oxa-bicyclo[3.1.0]hexan-2-one

: 201553-44-8
(1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Guidance literature:: With 2-hydroxypyridin; In toluene; for 48h; Heating;
DOI:10.1016/S0960-894X(97)10171-8

Reference yield:

: 100-39-0
benzyl bromide

: 201553-44-8
(1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / NaH, Bu₄NI / dimethylformamide / 4 h / 0 °C

2: 59 percent / 2-hydroxypyridine / toluene / 48 h / Heating

With 2-hydroxypyridin; tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0960-894X(97)10171-8

Reference yield:

: 201553-41-5
(1R,5S,6S)-6-Hydroxymethyl-3-oxa-bicyclo[3.1.0]hexan-2-one

: 201553-44-8
(1S,2S,3S)-2-Benzyloxymethyl-3-hydroxymethyl-cyclopropanecarboxylic acid ((S)-1-methylcarbamoyl-2-phenyl-ethyl)-amide

Guidance literature:: Multi-step reaction with 2 steps

1: 69 percent / NaH, Bu₄NI / dimethylformamide / 4 h / 0 °C

2: 59 percent / 2-hydroxypyridine / toluene / 48 h / Heating

With 2-hydroxypyridin; tetra-(n-butyl)ammonium iodide; sodium hydride; In N,N-dimethyl-formamide; toluene;
DOI:10.1016/S0960-894X(97)10171-8