4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Base Information

Chemical Name:4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide
CAS No.:425672-65-7
Molecular Formula:C₂₂H₃₅N₃O₅
Molecular Weight:421.537
Hs Code.:

Synonyms:4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Suppliers and Price of 4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

There total 5 articles about 4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

: 110-78-1
Propyl isocyanate

: 425672-62-4
2-[4-(3-hydrazinocarbonylpropyl)phenoxy]-2-methylpropionic acid tert-butyl ester

: 425672-65-7
4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Guidance literature:: In tetrahydrofuran; at 20 ℃; for 0.25h;
DOI:10.1021/op700040v

Reference yield:

: 23877-12-5
tert-butyl bromoisobutyrate

: 425672-65-7
4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Guidance literature:: Multi-step reaction with 3 steps

1: 27 g / K₂CO₃; MgSO₄ / dimethylformamide / 75 °C

2: hydrazine hydrate / methanol / 20 °C

3: tetrahydrofuran / 20 °C

With magnesium sulfate; potassium carbonate; hydrazine hydrate; In tetrahydrofuran; methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm034173l

Reference yield:

: 20637-08-5
4-(4-methoxyphenyl)butyric acid methyl ester

: 425672-65-7
4-[2-(1,1-dimethylethoxy)-1,1-dimethyl-2-oxoethoxy]benzenebutanoic acid 2-[(propylamino)carbonyl]hydrazide

Guidance literature:: Multi-step reaction with 4 steps

1: BBr₃ / CH₂Cl₂ / 1 h / 0 °C

2: 27 g / K₂CO₃; MgSO₄ / dimethylformamide / 75 °C

3: hydrazine hydrate / methanol / 20 °C

4: tetrahydrofuran / 20 °C

With boron tribromide; magnesium sulfate; potassium carbonate; hydrazine hydrate; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm034173l