2-[4-(3-Hydrazinocarbonylpropyl)phenoxy]-2-methyl-propionic acid tert-butyl ester

Base Information

Chemical Name:2-[4-(3-Hydrazinocarbonylpropyl)phenoxy]-2-methyl-propionic acid tert-butyl ester
CAS No.:425672-62-4
Molecular Formula:C₁₈H₂₈N₂O₄
Molecular Weight:336.431
Hs Code.:
DSSTox Substance ID:DTXSID00459978
Wikidata:Q82283876

Synonyms:425672-62-4;2-[4-(3-HYDRAZINOCARBONYLPROPYL)PHENOXY]-2-METHYL-PROPIONIC ACID TERT-BUTYL ESTER;2-[4-(3-Hydrazinocarbonyl-propyl)-phenoxy]-2-methyl-propionic acid tert-butyl ester;SCHEMBL3940025;DTXSID00459978;PULBKRUSVLYJRX-UHFFFAOYSA-N;tert-Butyl 2-(4-(4-hydrazinyl-4-oxobutyl)phenoxy)-2-methylpropanoate;tert-Butyl2-(4-(4-hydrazinyl-4-oxobutyl)phenoxy)-2-methylpropanoate

Suppliers and Price of 2-[4-(3-Hydrazinocarbonylpropyl)phenoxy]-2-methyl-propionic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-[4-(3-Hydrazinocarbonylpropyl)phenoxy]-2-methyl-propionic acid tert-butyl ester

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:336.20490738
Heavy Atom Count:24
Complexity:421

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)C(C)(C)OC1=CC=C(C=C1)CCCC(=O)NN

Technology Process of 2-[4-(3-Hydrazinocarbonylpropyl)phenoxy]-2-methyl-propionic acid tert-butyl ester

There total 4 articles about 2-[4-(3-Hydrazinocarbonylpropyl)phenoxy]-2-methyl-propionic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 20637-08-5
4-(4-methoxyphenyl)butyric acid methyl ester

: 425672-62-4
2-[4-(3-hydrazinocarbonylpropyl)phenoxy]-2-methylpropionic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: BBr₃ / CH₂Cl₂ / 1 h / 0 °C

2: 27 g / K₂CO₃; MgSO₄ / dimethylformamide / 75 °C

3: hydrazine hydrate / methanol / 20 °C

With boron tribromide; magnesium sulfate; potassium carbonate; hydrazine hydrate; In methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm034173l

Reference yield:

: 22320-10-1
methyl 4-(4-hydroxyphenyl)butanoate

: 425672-62-4
2-[4-(3-hydrazinocarbonylpropyl)phenoxy]-2-methylpropionic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 27 g / K₂CO₃; MgSO₄ / dimethylformamide / 75 °C

2: hydrazine hydrate / methanol / 20 °C

With magnesium sulfate; potassium carbonate; hydrazine hydrate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm034173l

Reference yield:

: 23877-12-5
tert-butyl bromoisobutyrate

: 425672-62-4
2-[4-(3-hydrazinocarbonylpropyl)phenoxy]-2-methylpropionic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 27 g / K₂CO₃; MgSO₄ / dimethylformamide / 75 °C

2: hydrazine hydrate / methanol / 20 °C

With magnesium sulfate; potassium carbonate; hydrazine hydrate; In methanol; N,N-dimethyl-formamide;
DOI:10.1021/jm034173l