2-benzyl-1,3-diphenylpropan-1-ol

Base Information

• Chemical Name: 2-benzyl-1,3-diphenylpropan-1-ol
• CAS No.: 24547-82-8
• Molecular Formula: C₂₂H₂₂O
• Molecular Weight: 302.416
• Mol file: 24547-82-8.mol

Synonyms:2-benzyl-1,3-diphenylpropan-1-ol

Chemical Property of 2-benzyl-1,3-diphenylpropan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzyl-1,3-diphenylpropan-1-ol

There total 17 articles about 2-benzyl-1,3-diphenylpropan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

1-Phenylethanol (98-85-1,13323-81-4) + benzyl alcohol (100-51-6,185532-71-2) → 2-benzyl-1,3-diphenylpropan-1-ol (24547-82-8)

Guidance literature:

1-Phenylethanol; benzyl alcohol; With C₃₉H₃₂Cl₃F₆IrN₂; potassium hydroxide; In toluene; at 140 ℃; for 16h;

In isopropyl alcohol; toluene; at 140 ℃; for 4h;

DOI:10.1021/acs.joc.0c01099

Reference yield: 69.0%

1,3-diphenyl-3-hydroxypropene (4663-33-6,62668-02-4,62839-70-7,116127-91-4,132014-29-0,136981-81-2,148616-45-9) + benzyl alcohol (100-51-6,185532-71-2) → dihydrochalcone (1083-30-3) + 2-benzyl-1,3-diphenyl-propan-1-one (6624-04-0) + 2-benzyl-1,3-diphenylpropan-1-ol (24547-82-8)

Guidance literature:

With C₂₇H₂₄Cl₃F₆IrN₂; potassium hydroxide; In toluene; at 140 ℃; for 8h; Reagent/catalyst;

DOI:10.1021/acs.joc.0c01099

Reference yield: 68.0%

1,3-diphenylpropan-1-ol (14097-24-6) + benzyl alcohol (100-51-6,185532-71-2) → dihydrochalcone (1083-30-3) + 2-benzyl-1,3-diphenyl-propan-1-one (6624-04-0) + 2-benzyl-1,3-diphenylpropan-1-ol (24547-82-8)

Guidance literature:

With C₂₇H₂₄Cl₃F₆IrN₂; potassium hydroxide; In toluene; at 140 ℃; for 8h; Reagent/catalyst;

DOI:10.1021/acs.joc.0c01099

upstream raw materials:

2-benzyl-3-phenylpropionaldehyde

acetophenone

benzyl alcohol

2-benzyl-1,3-diphenyl-1-propene

Downstream raw materials:

2-benzyl-1,3-diphenyl-propan-1-one

Refernces

• 1、 Sahoo, Apurba R.,Lalitha, Gummidi,Murugesh,Bruneau, Christian,Sharma, Gangavaram V.M.,Suresh, Surisetti,Achard, Mathieu. "Ruthenium phosphine-pyridone catalyzed cross-coupling of alcohols to form α-alkylated ketones". . p. 10727 - 10731. Retrieved 2018/05/31.