2,3-dimethoxy-1-methyl-4-vinylbenzene

Base Information

• Chemical Name: 2,3-dimethoxy-1-methyl-4-vinylbenzene
• CAS No.: 951161-56-1
• Molecular Formula: C₁₁H₁₄O₂
• Molecular Weight: 178.231
• Mol file: 951161-56-1.mol

Synonyms:2,3-dimethoxy-1-methyl-4-vinylbenzene

Chemical Property of 2,3-dimethoxy-1-methyl-4-vinylbenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-dimethoxy-1-methyl-4-vinylbenzene

There total 10 articles about 2,3-dimethoxy-1-methyl-4-vinylbenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

2-(diphenylphosphinyl)-4-methoxy-6-tert-butylphenol borane complex + Methyltriphenylphosphonium bromide (1779-49-3) → 2,3-dimethoxy-1-methyl-4-vinylbenzene (951161-56-1)

Guidance literature:

With lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; for 1h;

DOI:10.1002/chem.202101863

Reference yield: 92.0%

2,3-dimethoxy-4-methylbenzaldehyde (75889-47-3) + bis<(bromozincio)methylene>zinc → 2,3-dimethoxy-1-methyl-4-vinylbenzene (951161-56-1)

Guidance literature:

With boron trifluoride diethyl etherate; In tetrahydrofuran; at 20 ℃; for 3h;

DOI:10.1021/ol071228v

Reference yield: 92.0%

Methyltriphenylphosphonium bromide (1779-49-3) + 2,3-dimethoxy-4-methylbenzaldehyde (75889-47-3) → 2,3-dimethoxy-1-methyl-4-vinylbenzene (951161-56-1)

Guidance literature:

Methyltriphenylphosphonium bromide; With potassium hexamethylsilazane; In tetrahydrofuran; Inert atmosphere;

2,3-dimethoxy-4-methylbenzaldehyde; In tetrahydrofuran; for 16h; Reflux; Inert atmosphere;

DOI:10.1021/ja201321v

upstream raw materials:

2,3-dimethoxy-4-methylbenzaldehyde

1,2-dimethoxybenzene

1,2-dimethoxy-3-methylbenzene

Methyltriphenylphosphonium bromide

Downstream raw materials:

(R)-2-[1-(2,3-dimethoxy-4-methyl-phenyl)-ethyl]-4,4,5,5-tetramethyl-[1,3,2]-dioxaborolane

(S)-3-(2,3-dimethoxy-4-methylphenyl)butan-1-ol

(S)-1-(4-iodobutan-2-yl)-2,3-dimethoxy-4-methylbenzene

(S)-4-(2,3-dimethoxy-4-methylphenyl)pentanenitrile