(+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol

Base Information

• Chemical Name: (+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol
• CAS No.: 633336-02-4
• Molecular Formula: C₁₁H₁₅NOS₂
• Molecular Weight: 241.378
• Mol file: 633336-02-4.mol

Synonyms:(+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol

Chemical Property of (+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol

There total 1 articles about (+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 70.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + 2-Amino-1-phenylethanol (7568-93-6,1936-63-6) → (+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol (633336-02-4)

Guidance literature:

With sodium hydrogensulfide; In tetrahydrofuran; water; at 5 - 20 ℃; for 24.5h;

DOI:10.3987/com-04-10151

Reference yield: 98.0%

(+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol (633336-02-4) → tris[2-(1,3,5-dithiazinan-5-yl)-1-phenyl-ethanyl]-boric ester (1253239-80-3)

Guidance literature:

(+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol; With triethylamine; In toluene; at 20 ℃; for 0.5h; Inert atmosphere;

With boron trichloride; In hexane; toluene; at -78 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.molstruc.2010.07.019

Reference yield: 98.0%

boron trichloride (10294-34-5) + (+/-)-2-(1,3,5-dithiazinan-5-yl)-1-phenylethanol (633336-02-4) → tris[2-(1,3,5-dithiazinan-5-yl)-1-phenyl-ethanyl]-boric ester hemihydrate

Guidance literature:

With N(CH₂CH₃)3; In hexane; toluene; (under N2); ligand dissolved in toluene and N(CH2CH3)3 added, stirred atroom temp. for 30 min, cooled to -78°C, BCl3 in hexane added, st irred for 3 h at -78°C, warmed to room temp.; filtered, solvent evapd.; elem. anal.;

DOI:10.1016/j.molstruc.2010.07.019

upstream raw materials:

formaldehyd

2-Amino-1-phenylethanol

Downstream raw materials:

5-phenyl-1,3-oxazolidine

O-dimethylchloroaluminum-O-dimethylaluminum-1-phenyl-2-(1,3,5-dithiazinan-5-yl)ethanolate

bis[O-dimethylaluminum-1-phenyl-2-(1,3,5-dithiazinan-5-yl)ethanolate]

O-dimethylchloroaluminum-O-methylchloroaluminum-1-phenyl-2-(1,3,5-dithiazinan-5-yl)ethanolate

Refernces

• 1、 Colorado-Peralta, Raúl,Xotlanihua-Flores, Alfonso,Gálvez-Ruíz, Juan Carlos,Sánchez-Ruíz, Sonia A.,Contreras, Rosalinda,Flores-Parra, Angelina. "Tripodal molecules derived from ethanoldithiazinanes centered on boron and phosphorus atoms. Structural analyses by NMR and HF/6-31G(d) calculations". experimental part. p. 21 - 33. Retrieved 2011/01/06.