1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

Base Information

Chemical Name:1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]
CAS No.:1554015-71-2
Molecular Formula:C₂₆H₃₀F₃N₃OS
Molecular Weight:489.605
Hs Code.:

Synonyms:1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

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Chemical Property of 1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

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Technology Process of 1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

There total 1 articles about 1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 1554015-60-9
2-[7-methoxy-1'-neopentyl-4-(trifluoromethyl)-1,2-dihydrospiro[indole-3,4'-piperidine]-1-yl]aniline

: 102368-13-8
1,1'-Thiocarbonyldi-2(1H)-pyridone

: 1554015-71-2
1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

Guidance literature:: In dichloromethane; at 23 ℃; for 5h;

Reference yield: 54.2%

: 1554015-71-2
1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

: 613-94-5
benzoic acid hydrazide

: 1554015-72-3
N-(2-(7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]-1-yl)phenyl)-5-phenyl-1,3,4-thiadiazol-2-amine

Guidance literature:: 1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]; benzoic acid hydrazide; In dichloromethane; at 23 ℃; for 18h;

With sulfuric acid; In dichloromethane; for 0.5h;

Reference yield:

: 1554015-71-2
1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]

: 1554015-75-6
N-(2-(4-chloro-7-methoxy-1'-neopentylspiro[indoline-3,4'-piperidine]-1-yl)phenyl)hydrazinecarbothioamide

Guidance literature:: 1-(2-isothiocyanatophenyl)-7-methoxy-1'-neopentyl-4-(trifluoromethyl)spiro[indoline-3,4'-piperidine]; With t-butoxycarbonylhydrazine; In dichloromethane; at 23 ℃; for 18h;

With trifluoroacetic acid; In dichloromethane; for 2h;