N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Base Information

Chemical Name:N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate
CAS No.:1360054-66-5
Molecular Formula:C₃₀H₃₃N₅O₆*H₂O₄S
Molecular Weight:657.701
Hs Code.:

Synonyms:N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Suppliers and Price of N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

There total 5 articles about N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)adenosine

: 77-76-9
2,2-dimethoxy-propane

: 1360054-66-5
N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Guidance literature:: With sulfuric acid; In acetone; at 20 ℃; for 0.833333h; Inert atmosphere; Large scale reaction;
DOI:10.1021/op200365n

Reference yield:

: 264608-14-2
2-chloro-N-(2,2-diphenylethyl)-9-(tetrahydro-2H-pyran-2-yl)-9H-purin-6-amine

: 1360054-66-5
N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Guidance literature:: Multi-step reaction with 6 steps

1: 1,1'-bis-(diphenylphosphino)ferrocene; palladium diacetate; sodium carbonate / 105 °C / 15001.5 Torr / Autoclave

2: trifluoroacetic acid / ethanol / 20 h / 50 °C / Inert atmosphere

3: 4-methyl-morpholine / 1,2-dimethoxyethane / 50 - 60 °C / Inert atmosphere; Large scale reaction

4: 1,2-dimethoxyethane / 1.75 h / 65 °C / Inert atmosphere; Large scale reaction

5: ethanol; 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 °C / Inert atmosphere

6: sulfuric acid / acetone / 0.83 h / 20 °C / Inert atmosphere; Large scale reaction

With 4-methyl-morpholine; 1,1'-bis-(diphenylphosphino)ferrocene; ethanol; sulfuric acid; palladium diacetate; sodium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; trifluoroacetic acid; In 1,2-dimethoxyethane; ethanol; acetone;
DOI:10.1021/op200365n

Reference yield:

: ethyl 6-[(2,2-diphenylethyl)amino]-9H-purine-2-carboxylate

: 1360054-66-5
N-(2,2-diphenylethyl)-2-(ethoxycarbonyl)-2',3'-O-isopropylidene-adenosine hydrogen sulfate

Guidance literature:: Multi-step reaction with 4 steps

1: 4-methyl-morpholine / 1,2-dimethoxyethane / 50 - 60 °C / Inert atmosphere; Large scale reaction

2: 1,2-dimethoxyethane / 1.75 h / 65 °C / Inert atmosphere; Large scale reaction

3: ethanol; 1,8-diazabicyclo[5.4.0]undec-7-ene / 20 °C / Inert atmosphere

4: sulfuric acid / acetone / 0.83 h / 20 °C / Inert atmosphere; Large scale reaction

With 4-methyl-morpholine; ethanol; sulfuric acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; In 1,2-dimethoxyethane; acetone;
DOI:10.1021/op200365n