(1,2-dimethyl-1H-imidazol-5-yl)methanol

Base Information

• Chemical Name: (1,2-dimethyl-1H-imidazol-5-yl)methanol
• CAS No.: 24021-93-0
• Molecular Formula: C₆H₁₀N₂O
• Molecular Weight: 126.158
• NSC Number: 195980
• DSSTox Substance ID: DTXSID00307869
• Wikidata: Q82055451
• Mol file: 24021-93-0.mol

Synonyms:(1,2-dimethyl-1H-imidazol-5-yl)methanol;24021-93-0;(2,3-dimethylimidazol-4-yl)methanol;NSC195980;SCHEMBL859147;DTXSID00307869;CISHHWIYBOSLHY-UHFFFAOYSA-N;MFCD09697178;AKOS003655599;NSC-195980;BB 0221029;CS-0378520

Chemical Property of (1,2-dimethyl-1H-imidazol-5-yl)methanol

Chemical Property:

• Vapor Pressure: 0.000233mmHg at 25°C
• Boiling Point: 312°C at 760 mmHg
• Flash Point: 142.5°C
• Density: 1.13g/cm³
• XLogP3: -0.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 126.079312947
• Heavy Atom Count: 9
• Complexity: 97.1

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=NC=C(N1C)CO

Technology Process of (1,2-dimethyl-1H-imidazol-5-yl)methanol

There total 4 articles about (1,2-dimethyl-1H-imidazol-5-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

1,2-dimethyl-1H-imidazole (1739-84-0) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → (1,2-dimethyl-1H-imidazol-5-yl)methanol (24021-93-0)

Guidance literature:

With sodium acetate; acetic acid; for 72h; Heating;

Reference yield:

1,2-dimethyl-1H-imidazole-5-carbaldehyde (24134-12-1) → (1,2-dimethyl-1H-imidazol-5-yl)methanol (24021-93-0)

Guidance literature:

With methanol; sodium tetrahydroborate; at 0 - 20 ℃;

Reference yield:

1,2-dimethyl-1H-imidazole (1739-84-0) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → (1,2-dimethyl-1H-imidazol-4-yl)methanol (1038828-36-2) + C9H16N2 + (1,2-dimethyl-1H-imidazol-5-yl)methanol (24021-93-0)

Guidance literature:

With sodium acetate; In water; acetic acid; at 90 - 96 ℃;

DOI:10.1021/op9002505

upstream raw materials:

1,2-dimethyl-1H-imidazole

formaldehyd

1,2-dimethyl-1H-imidazole-5-carbaldehyde

Downstream raw materials:

5-bromo-1,2-dimethyl-1H-imidazole

4,5-dibromo-2-methyl-1-methylimidazole

1,2-dimethyl-1H-imidazole-5-carbaldehyde