ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

Base Information Edit

Chemical Name:ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre
CAS No.:1041853-11-5
Molecular Formula:C₁₃H₁₃ClN₂O₄
Molecular Weight:296.71
Hs Code.:
Mol file:1041853-11-5.mol

Synonyms:ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

Suppliers and Price of ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre Edit

Chemical Property:

Boiling Point:437.7±55.0 °C(Predicted)
Density:1.322±0.06 g/cm3(Predicted)

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

There total 6 articles about ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 1041853-08-0
ethyl 6,7-dimethoxy-4-oxo-1,4-dihydrocinnoline-3-carboxylatre

: 1041853-11-5
ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

Guidance literature:: With trichlorophosphate; for 2h; Heating / reflux;

Reference yield:

: 4101-30-8
2-amino-4,5-dimethoxyacetophenone

: 1041853-11-5
ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride; sodium nitrite / water / 0 °C

2: sodium hydride / tetrahydrofuran / Reflux

3: trifluoroacetic acid / 0 °C

4: trichlorophosphate / Reflux

With hydrogenchloride; sodium hydride; trifluoroacetic acid; sodium nitrite; trichlorophosphate; In tetrahydrofuran; water;
DOI:10.1016/j.bmcl.2011.01.033

Reference yield:

: 1284175-28-5
C₁₄H₁₉N₃O₃

: 1041853-11-5
ethyl 4-chloro-6,7-dimethoxycinnoline-3-carboxylatre

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydride / tetrahydrofuran / Reflux

2: trifluoroacetic acid / 0 °C

3: trichlorophosphate / Reflux

With sodium hydride; trifluoroacetic acid; trichlorophosphate; In tetrahydrofuran;
DOI:10.1016/j.bmcl.2011.01.033