(R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

Base Information

Chemical Name:(R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile
CAS No.:1394806-90-6
Molecular Formula:C₁₉H₂₄N₆
Molecular Weight:336.44
Hs Code.:

Synonyms:(R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

Suppliers and Price of (R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

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Chemical Property of (R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

Chemical Property:

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Technology Process of (R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

There total 6 articles about (R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 334618-23-4
3-(R)-aminopiperidine dihydrochloride

: 1394321-67-5
3-(4-chloro-6-propylpyrimidin-2-ylamino)benzonitrile

: 1394806-90-6
(R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

Guidance literature:: With sodium hydrogencarbonate; In ethanol; at 130 ℃; Molecular sieve;

Reference yield:

: (R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile dihydrochloride

: 1394806-90-6
(R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

Guidance literature:: With sodium hydrogencarbonate; In water;

Reference yield:

: 51-52-5
propylthiouracil

: 1394806-90-6
(R)-3-[4-(3-aminopiperidin-1-yl)-6-propylpyrimidin-2-ylamino]benzonitrile

Guidance literature:: Multi-step reaction with 4 steps

1: sodium hydroxide / water / 20 °C

2: 160 °C

3: trichlorophosphate / 2 h / 110 °C

4: sodium hydrogencarbonate / ethanol / 130 °C / Molecular sieve

With sodium hydrogencarbonate; sodium hydroxide; trichlorophosphate; In ethanol; water;